Department of Dermatology and Venereology, Koç University School of Medicine, Istanbul, Turkey.
School of Medicine, Koç University, Istanbul, Turkey.
Int J Dermatol. 2024 Aug;63(8):987-998. doi: 10.1111/ijd.17101. Epub 2024 Feb 26.
Hidradenitis suppurativa (HS) is a chronic condition that can overwhelm patients, and the effectiveness of supplementary dietary treatments remains uncertain. The primary aim of this review is to explore the connection between diet and HS progression. However, it is imperative to note that the evidence supporting a substantial role of the diet in HS remains weak. Dietary alterations alone should not be considered independent solutions for managing HS. Medical therapy continues to be indispensable for adequate treatment. Research indicates that the Mediterranean lifestyle and diet may provide cost-effective and beneficial adjustments when combined with traditional therapies. Conversely, foods with a high glycemic index and dairy could worsen HS symptoms, conceivably through mechanisms linked to insulin resistance and inflammation. Zinc, known for its antioxidant properties, shows promise as an adjunct therapy. Moreover, evidence suggests a connection between vitamin D deficiency and HS severity, although the findings are inconclusive. Brewer's yeast-free diet, B12 supplementation, intermittent fasting, and reducing the intake of refined sugar and dairy merit further investigation. In conclusion, this review highlights the need for additional research because of the lack of standardized reporting of clinical effects in the studies under scrutiny. A deeper exploration of the pathophysiology focusing on dietary modifications and their potential associations with HS severity is essential. Furthermore, it is crucial to recognize that patients' willingness to experiment with new diets makes them vulnerable to fraudulent interventions, highlighting the importance of evidence-based dietary guidance.
化脓性汗腺炎(HS)是一种会使患者不堪重负的慢性疾病,补充性饮食治疗的效果仍不确定。本综述的主要目的是探讨饮食与 HS 进展之间的关系。然而,必须指出的是,支持饮食在 HS 中起重要作用的证据仍然薄弱。仅通过改变饮食不应被视为独立的 HS 管理方法。医学治疗仍然是充分治疗所必需的。研究表明,地中海生活方式和饮食与传统疗法相结合,可能提供具有成本效益的有益调整。另一方面,高血糖指数和乳制品的食物可能会通过与胰岛素抵抗和炎症相关的机制使 HS 症状恶化。具有抗氧化特性的锌作为辅助治疗显示出前景。此外,有证据表明维生素 D 缺乏与 HS 严重程度之间存在关联,但结果尚无定论。无酿酒酵母饮食、B12 补充、间歇性禁食以及减少精制糖和乳制品的摄入值得进一步研究。总之,由于研究中缺乏对临床效果的标准化报告,因此需要进一步研究。需要深入探讨饮食改变及其与 HS 严重程度的潜在关联的病理生理学。此外,必须认识到,患者愿意尝试新的饮食方法,使他们容易受到欺诈性干预,这突出了基于证据的饮食指导的重要性。
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