Fries A S
Lab Anim. 1979 Apr;13(2):143-7. doi: 10.1258/002367779780943486.
The correlation between serum antibody titre and resistance to challenge infection with Bacillus piliformis was studied in naturally infected mice, in experimentally infected but recovered mice, and in mice treated with antigen prepared from infected livers. Irrespective of the way in which the antibodies were acquired resistance to infection was found to be related to the immunofluorescence antibody titre found. Experimentally infected but recovered mice, as well as rats with persistent antibodies to Bacillus piliformis, were given prednisolone in order to activate a possible persistent infection. Bacillus piliformis was detected in the rats, but not in the mice.
在自然感染的小鼠、实验感染后已恢复的小鼠以及用感染肝脏制备的抗原处理过的小鼠中，研究了血清抗体滴度与对梨形芽孢杆菌攻击感染的抵抗力之间的相关性。无论抗体是如何获得的，都发现对感染的抵抗力与所测得的免疫荧光抗体滴度有关。对实验感染后已恢复的小鼠以及对梨形芽孢杆菌有持续抗体的大鼠给予泼尼松龙，以激活可能存在的持续性感染。在大鼠中检测到了梨形芽孢杆菌，但在小鼠中未检测到。
