无特定病原体（SPF）群体中抗毛发状芽孢杆菌抗体的检测以及小鼠经胎盘感染毛发状芽孢杆菌的实验研究

Demonstration of antibodies to Bacillus piliformis in SPF colonies and experimental transplacental infection by Bacillus piliformis in mice.

作者信息

Fries A S

出版信息

Lab Anim. 1978 Jan;12(1):23-6. doi: 10.1258/002367778780953332.

Abstract

Antibodies to Bacillus piliformis were demonstrated by the immunofluorescence antibody technique in sera from mice and rabbits from SPF breeding colonies. Mice in various stages of pregnancy were experimentally infected with Bacillus piliformis and killed 2 to 3 days later. The organism was demonstrated in the uterus, foetal membranes and in the liver of the foetuses. Infection was not limited to any particular stage of pregnancy.

摘要

采用免疫荧光抗体技术在无特定病原体（SPF）繁殖群体的小鼠和家兔血清中检测到了针对毛发状芽孢杆菌的抗体。处于不同妊娠阶段的小鼠经实验感染毛发状芽孢杆菌，并在2至3天后处死。在子宫、胎膜和胎儿肝脏中发现了该微生物。感染并不局限于妊娠的任何特定阶段。