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二级痴呆预防计划在实践中如何发挥作用:APPLE-Tree 计划的实施前研究。

How might secondary dementia prevention programs work in practice: a pre-implementation study of the APPLE-Tree program.

机构信息

Centre for Psychiatry and Mental Health, Wolfson Institute of Population Health, Queen Mary University of London, London, UK.

Department of Health and Community Sciences, University of Exeter Medical School , Exeter, UK.

出版信息

BMC Geriatr. 2024 Feb 26;24(1):188. doi: 10.1186/s12877-024-04762-3.

Abstract

BACKGROUND

Over 850,000 people in the UK currently have dementia, and that number is expected to grow rapidly. One approach that may help slow or prevent this growth is personalized dementia prevention. For most people, this will involve targeted lifestyle changes. These approaches have shown promise in trials, but as of yet, the evidence for how to scale them to a population level is lacking. In this pre-implementation study, we aimed to explore stakeholder perspectives on developing system-readiness for dementia prevention programs. We focused on the APPLE-Tree program, one of several low-intensity, lifestyle-based dementia prevention interventions currently in clinical trials.

METHODS

We conducted semi-structured interviews with health and social care professionals without previous experience with the APPLE-Tree program, who had direct care or managerial experience in services for older adults with memory concerns, without a dementia diagnosis. We used the Consolidated Framework for Implementation Research to guide interviews and thematic analysis.

RESULTS

We interviewed 26 stakeholders: commissioners and service managers (n = 15) and frontline workers (n = 11) from eight NHS and 11 third sector organizations throughout England. We identified three main themes: (1) favorable beliefs in the effectiveness of dementia prevention programs in enhancing cognition and wellbeing and their potential to fill a service gap for people with memory concerns, (2) challenges related to funding and capacity to deliver such programs at organizations without staff capacity or higher prioritization of dementia services, and (3) modifications to delivery and guidance required for compatibility with organizations and patients.

CONCLUSION

This study highlights likely challenges in scale-up if we are to make personalized dementia prevention widely available. This will only be possible with increased funding of dementia prevention activities; integrated care systems, with their focus on prevention, may enable this. Scale-up of dementia prevention programs will also require clear outlines of their core and adaptable components to fit funding, patient, and facilitator needs.

摘要

背景

目前,英国有超过 85 万人患有痴呆症,而且这个数字预计还会迅速增长。一种可能有助于减缓或预防这种增长的方法是个性化的痴呆症预防。对大多数人来说,这将涉及有针对性的生活方式改变。这些方法在试验中显示出了前景,但截至目前,关于如何将其推广到人群层面的证据还很缺乏。在这项实施前研究中,我们旨在探讨利益相关者对开发痴呆症预防计划系统准备度的看法。我们专注于 APPLE-Tree 计划,这是目前正在临床试验中的几种低强度、基于生活方式的痴呆症预防干预措施之一。

方法

我们对没有 APPLE-Tree 计划先前经验的卫生和社会保健专业人员进行了半结构化访谈,这些专业人员在有记忆问题的老年人服务中具有直接护理或管理经验,但没有痴呆症诊断。我们使用实施研究综合框架来指导访谈和主题分析。

结果

我们采访了 26 位利益相关者:来自英格兰 8 个 NHS 和 11 个第三部门组织的决策者和服务经理(n=15)和一线工作者(n=11)。我们确定了三个主要主题:(1)相信痴呆症预防计划在提高认知和幸福感方面的有效性,以及它们为有记忆问题的人填补服务空白的潜力,(2)在没有员工能力或更高的痴呆症服务优先级的组织中提供此类计划的资金和能力方面的挑战,以及(3)为与组织和患者兼容所需的交付和指导的修改。

结论

如果我们要广泛提供个性化的痴呆症预防,这项研究强调了在扩大规模方面可能存在的挑战。只有通过增加痴呆症预防活动的资金,才能实现这一目标;以预防为重点的综合护理系统可能会使这成为可能。痴呆症预防计划的扩大还需要明确其核心和可适应部分的大纲,以适应资金、患者和促进者的需求。

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