Obstetrical department, Changzhou Women and Children Health Hospital, Nanjing Medical University, Changzhou, Jiangsu, China.
BMC Pregnancy Childbirth. 2024 Feb 26;24(1):164. doi: 10.1186/s12884-024-06313-5.
The causes of some stillbirths are unclear, and additional work must be done to investigate the risk factors for stillbirths.
To apply the International Classification of Disease-10 (ICD-10) for antepartum stillbirth at a referral center in eastern China.
Antepartum stillbirths were grouped according to the cause of death according to the International Classification of Disease-10 (ICD-10) criteria. The main maternal condition at the time of antepartum stillbirth was assigned to each patient.
Antepartum stillbirths were mostly classified as fetal deaths of unspecified cause, antepartum hypoxia. Although more than half of the mothers were without an identified condition at the time of the antepartum stillbirth, where there was a maternal condition associated with perinatal death, maternal medical and surgical conditions and maternal complications during pregnancy were most common. Of all the stillbirths, 51.2% occurred between 28 and 37 weeks of gestation, the main causes of stillbirth at different gestational ages also differed. Autopsy and chromosomal microarray analysis (CMA) were recommended in all stillbirths, but only 3.6% received autopsy and 10.5% underwent chromosomal microarray analysis.
The ICD-10 is helpful in classifying the causes of stillbirths, but more than half of the stillbirths in our study were unexplained; therefore, additional work must be done. And the ICD-10 score may need to be improved, such as by classifying stillbirths according to gestational age. Autopsy and CMA could help determine the cause of stillbirth, but the acceptance of these methods is currently low.
一些死胎的原因尚不清楚，必须进一步开展工作，以调查死胎的危险因素。
在中国东部的一家转诊中心应用国际疾病分类第 10 版（ICD-10）对产前死胎进行分类。
根据国际疾病分类第 10 版（ICD-10）标准，根据死因将产前死胎进行分组。每位患者的主要产前死胎时的母体情况均被分配到相应的组别。
产前死胎大多被归类为不明原因的胎儿死亡、产前缺氧。尽管超过一半的母亲在产前死胎时没有明确的情况，但与围产儿死亡相关的母体情况中，孕产妇医疗和外科情况以及妊娠期间的孕产妇并发症最为常见。在所有死胎中，51.2%发生在 28 至 37 孕周之间，不同胎龄的死胎主要原因也不同。建议对所有死胎进行尸检和染色体微阵列分析（CMA），但只有 3.6%接受了尸检，10.5%进行了染色体微阵列分析。
ICD-10 有助于对死胎的原因进行分类，但我们研究中的一半以上的死胎原因不明；因此，必须进一步开展工作。并且 ICD-10 评分可能需要改进，例如根据胎龄对死胎进行分类。尸检和 CMA 有助于确定死胎的原因，但目前这些方法的接受度较低。
