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本文引用的文献

1
Assessment of a feed additive containing  NCIMB 11181 (Lactiferm®) for weaned piglets, calves for fattening and calves for rearing for the renewal of its authorisation (Chr. Hansen A/S).对一种含有NCIMB 11181(Lactiferm®)的饲料添加剂进行评估,该添加剂用于断奶仔猪、育肥牛犊和育成牛犊,以更新其授权(科汉森公司)。
EFSA J. 2023 Dec 1;21(12):e8466. doi: 10.2903/j.efsa.2023.8466. eCollection 2023 Dec.
2
EFSA statement on the requirements for whole genome sequence analysis of microorganisms intentionally used in the food chain.欧洲食品安全局关于食物链中有意使用的微生物全基因组序列分析要求的声明。
EFSA J. 2021 Jul 28;19(7):e06506. doi: 10.2903/j.efsa.2021.6506. eCollection 2021 Jul.
3
Guidance on the assessment of the safety of feed additives for the environment.饲料添加剂对环境安全性的评估指南。
EFSA J. 2019 Apr 5;17(4):e05648. doi: 10.2903/j.efsa.2019.5648. eCollection 2019 Apr.
4
Guidance on the assessment of the efficacy of feed additives.饲料添加剂功效评估指南。
EFSA J. 2018 May 7;16(5):e05274. doi: 10.2903/j.efsa.2018.5274. eCollection 2018 May.
5
Guidance on the characterisation of microorganisms used as feed additives or as production organisms.用作饲料添加剂或生产生物的微生物特性鉴定指南。
EFSA J. 2018 Mar 28;16(3):e05206. doi: 10.2903/j.efsa.2018.5206. eCollection 2018 Mar.
6
Guidance on the identity, characterisation and conditions of use of feed additives.饲料添加剂的标识、特性及使用条件指南。
EFSA J. 2017 Oct 17;15(10):e05023. doi: 10.2903/j.efsa.2017.5023. eCollection 2017 Oct.
7
Guidance on the assessment of the safety of feed additives for the target species.目标物种饲料添加剂安全性评估指南。
EFSA J. 2017 Oct 17;15(10):e05021. doi: 10.2903/j.efsa.2017.5021. eCollection 2017 Oct.

一种由NCIMB 11181(Lactiferm®)组成的饲料添加剂对育肥鸡或产蛋鸡、其他育肥或产蛋家禽品种以及观赏鸟的安全性和有效性(科汉森公司)

Safety and efficacy of a feed additive consisting of  NCIMB 11181 (Lactiferm®) for chickens for fattening or reared for laying, other poultry species for fattening or reared for laying, and ornamental birds (Chr. Hansen A/S).

作者信息

Bampidis Vasileios, Azimonti Giovanna, Bastos Maria de Lourdes, Christensen Henrik, Durjava Mojca, Dusemund Birgit, Kouba Maryline, López-Alonso Marta, López Puente Secundino, Marcon Francesca, Mayo Baltasar, Pechová Alena, Petkova Mariana, Ramos Fernando, Villa Roberto Edoardo, Woutersen Ruud, Anguita Montserrat, Ortuňo Casanova Jordi, Pettenati Elisa, Tarrés-Call Jordi

出版信息

EFSA J. 2024 Feb 26;22(2):e8623. doi: 10.2903/j.efsa.2024.8623. eCollection 2024 Feb.

DOI:10.2903/j.efsa.2024.8623
PMID:38410146
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10895453/
Abstract

Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a feed additive consisting of NCIMB 11181 (Lactiferm®) as a zootechnical additive (gut flora stabiliser) for chickens for fattening, chickens reared for laying, other poultry species for fattening or reared for laying, and ornamental birds. The additive is available in two formulations: Lactiferm WS200 and Lactiferm Basic 50. The FEEDAP Panel concluded that the use of the additive is safe for chickens for fattening or reared for laying, other poultry species for fattening or reared for laying, and ornamental birds. The Panel also concluded that the use of the feed additive is safe for consumers, and the environment. Lactiferm WS200 is not irritant to skin or eyes. Owing to the proteinaceous nature of the active agent, both formulations of the additive are considered respiratory sensitisers. It was not possible, however, to conclude on the irritancy potential for skin and eyes of the Lactiferm Basic 50 formulation or on the potential of both formulations of the additive to cause skin sensitisation. The efficacy studies submitted did not allow to draw a conclusion on the efficacy of the additive for the target species. Lactiferm® is considered compatible with the coccidiostats monensin sodium and decoquinate.

摘要

应欧盟委员会的要求,欧洲食品安全局被要求就一种由NCIMB 11181(Lactiferm®)组成的饲料添加剂作为育肥鸡、产蛋鸡、其他育肥或产蛋家禽品种以及观赏鸟的动物营养添加剂(肠道菌群稳定剂)的安全性和有效性发表科学意见。该添加剂有两种制剂:Lactiferm WS200和Lactiferm Basic 50。饲料添加剂和动物营养产品专家委员会得出结论,该添加剂对育肥鸡或产蛋鸡、其他育肥或产蛋家禽品种以及观赏鸟的使用是安全的。该委员会还得出结论,该饲料添加剂对消费者和环境的使用是安全的。Lactiferm WS200对皮肤或眼睛无刺激性。由于活性剂的蛋白质性质,该添加剂的两种制剂均被视为呼吸道致敏剂。然而,无法就Lactiferm Basic 50制剂对皮肤和眼睛的刺激潜力或该添加剂的两种制剂引起皮肤致敏的潜力得出结论。提交的功效研究无法就该添加剂对目标物种的功效得出结论。Lactiferm®被认为与抗球虫药莫能菌素钠和地考喹酯相容。