Liu Xinchao, Xing Hao, Lin Jing, Sun Jian, Wang Yu, Liu Yaxu, Cao Wei, Liu Zhengyin, Li Taisheng
Department of Infectious Disease, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, People's Republic of China.
Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, People's Republic of China.
Infect Drug Resist. 2024 Feb 22;17:709-718. doi: 10.2147/IDR.S432697. eCollection 2024.
is prevalent in South Asia. Latent infection of travellers make the diagnosis difficult. There are similarities in clinical manifestations between infection and lymphoma. Brain abscess is a rare form of infection.
We reported a very rare case of a 19-year-old man with HIV infection who suffered from a brain mass and lymphadenopathy. His blood culture, bone marrow culture and sputum culture all grew . One month after treatment with voriconazole, the symptoms improved except brain mass. Surgical incision of the brain mass showed a compact mass, and pathological analysis showed the coexisting abscess and lymphoma. The patient is currently in a stable condition after receiving antifungal therapy and chemotherapy.
Based on a case report of a traveller who suffered from a brain mass of abscess and lymphoma after a visit to an endemic area, this review summarized the cases where there was confusion between lymphoma and the brain abscess of infection can be found globally due to the increasing number of international travels. infection and lymphoma had similar characteristics which is easy to misdiagnose in clinic. Infection may also be accompanied by tumors, especially in patients infected with HIV. The manifestations and imaging of brain abscess of were not characteristic in different patients.
在南亚地区较为普遍。旅行者的潜伏感染使得诊断困难。感染与淋巴瘤的临床表现存在相似之处。脑脓肿是感染的一种罕见形式。
我们报告了一例非常罕见的病例，一名19岁的HIV感染男性患有脑肿块和淋巴结病。他的血培养、骨髓培养和痰培养均培养出[病原体名称未给出]。使用伏立康唑治疗一个月后，除脑肿块外症状有所改善。脑肿块手术切除显示为致密肿块，病理分析显示同时存在[病原体名称未给出]脓肿和淋巴瘤。患者在接受抗真菌治疗和化疗后目前病情稳定。
基于一例前往流行地区后出现[病原体名称未给出]脓肿和淋巴瘤脑肿块的旅行者病例报告，本综述总结了由于国际旅行增加，全球范围内淋巴瘤与[病原体名称未给出]感染性脑脓肿之间存在混淆的病例。[病原体名称未给出]感染和淋巴瘤具有相似特征，在临床上容易误诊。感染也可能伴有肿瘤，尤其是在HIV感染患者中。不同患者[病原体名称未给出]脑脓肿的表现和影像学特征不典型。
