Singh Annapoorna, Atallah Sarah, Al-Shyoukh Ahmad, DaCunha Matthew, Mizusawa Masako
Department of Internal Medicine, University of Missouri Kansas City, Kansas City, MO, United States.
University of Missouri Kansas City School of Medicine, Kansas City, MO, United States.
IDCases. 2020 May 16;21:e00824. doi: 10.1016/j.idcr.2020.e00824. eCollection 2020.
is an opportunistic fungal infection seen in immunocompromised patients including those with HIV/AIDS. It is usually seen in patients who live in or are from tropical Asia. In HIV patients, oropharyngeal and laryngeal lesions are usually part of disseminated infection. We describe a case of 63-year-old Vietnamese male with history of HIV/AIDS who presented with localized tonsillar infection without disseminated disease. Imaging studies showed a right tonsillar mass with right cervical lymphadenopathy which was initially thought to be malignancy. The patient underwent biopsy of the mass and histology showed noncaseating granulomas on hematoxylin and eosin stain as well as yeast on Grocott methenamine silver stain. Fungal culture of the biopsy specimen grew suede-like grayish-white colonies with diffuse underlying deep red color pigment which was identified as The patient was treated with intravenous liposomal amphotericin B and achieved resolution of symptoms and tonsillar mass. In HIV/AIDS patients who are either from endemic regions or with history of travel to endemic areas particularly Southeast Asia and China, infection should be considered in differential diagnoses of a tonsillar mass.
是一种在免疫功能低下患者中出现的机会性真菌感染，包括那些患有艾滋病毒/艾滋病的患者。它通常见于居住在热带亚洲或来自热带亚洲的患者。在艾滋病毒患者中，口咽和喉部病变通常是播散性感染的一部分。我们描述了一例63岁的越南男性艾滋病毒/艾滋病患者，其表现为局限性扁桃体感染，无播散性疾病。影像学检查显示右侧扁桃体肿物伴右侧颈部淋巴结肿大，最初被认为是恶性肿瘤。患者接受了肿物活检，苏木精和伊红染色显示非干酪样肉芽肿，Grocott六胺银染色显示酵母。活检标本的真菌培养长出绒面革样灰白色菌落，其下有弥漫性深红色色素，被鉴定为……患者接受了静脉注射脂质体两性霉素B治疗，症状和扁桃体肿物消退。对于来自流行地区或有前往流行地区（特别是东南亚和中国）旅行史的艾滋病毒/艾滋病患者，在扁桃体肿物的鉴别诊断中应考虑感染。
