School of Pharmacy and Life Sciences, Centurion University of Technology and Management, Bhubaneswar, Odisha 752050, India.
State Forensic Science Laboratory, Bhubaneswar, Odisha 751010, India.
ACS Appl Bio Mater. 2024 Mar 18;7(3):1336-1361. doi: 10.1021/acsabm.3c01064. Epub 2024 Feb 27.
Over the past decade, nanotechnology has seen extensive integration into biomedical applications, playing a crucial role in biodetection, drug delivery, and diagnostic imaging. This is especially important in reproductive health care, which has become an emerging and significant area of research. Global concerns have intensified around disorders such as infertility, endometriosis, ectopic pregnancy, erectile dysfunction, benign prostate hyperplasia, sexually transmitted infections, and reproductive cancers. Nanotechnology presents promising solutions to address these concerns by introducing innovative tools and techniques, facilitating early detection, targeted drug delivery, and improved imaging capabilities. Through the utilization of nanoscale materials and devices, researchers can craft treatments that are not only more precise but also more effective, significantly enhancing outcomes in reproductive healthcare. Looking forward, the future of nanotechnology in reproductive medicine holds immense potential for reshaping diagnostics, personalized therapies, and fertility preservation. The utilization of nanotechnology-driven drug delivery systems is anticipated to elevate treatment effectiveness, minimize side effects, and offer patients therapies that are not only more precise but also more efficient. This review aims to delve into the various types, properties, and preparation techniques of nanocarriers specifically designed for drug delivery in the context of reproductive disorders, shedding light on the current landscape and potential future directions in this dynamic field.
在过去的十年中，纳米技术已经广泛应用于生物医学领域，在生物检测、药物输送和诊断成像方面发挥着关键作用。这在生殖保健领域尤为重要，生殖保健已成为一个新兴且重要的研究领域。全球对不孕、子宫内膜异位症、异位妊娠、勃起功能障碍、良性前列腺增生、性传播感染和生殖系统癌症等疾病的关注日益加剧。纳米技术通过引入创新工具和技术，为解决这些问题提供了有前景的解决方案，有助于早期检测、靶向药物输送和改善成像能力。通过利用纳米级材料和设备，研究人员可以设计出不仅更精确而且更有效的治疗方法，从而显著改善生殖保健的结果。展望未来，纳米技术在生殖医学中的应用具有巨大的潜力，可以重塑诊断、个性化治疗和生育力保存。预计纳米技术驱动的药物输送系统的应用将提高治疗效果，减少副作用，并为患者提供不仅更精确而且更有效的治疗方法。本综述旨在深入探讨专门用于生殖障碍药物输送的各种类型、性质和制备技术的纳米载体，阐明这一充满活力的领域的当前格局和潜在未来方向。
