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G. 卡尔·胡伯(1865 - 1934):密歇根州周围神经损伤与再生领域的先驱

G. Carl Huber (1865-1934): A Michigan Pioneer in Peripheral Nerve Injury and Regeneration.

作者信息

Hooten Kristopher G, Puffer Ross C, Kline David G, McGillicuddy John E, Yang Lynda J-S

机构信息

Division of Neurosurgery, Walter Reed Army Medical Center, Bethesda, Maryland, USA.

Department of Neurosurgery, Louisiana State University, New Orleans, Louisiana, USA.

出版信息

Neurosurgery. 2024 Feb 27. doi: 10.1227/neu.0000000000002870.

DOI:10.1227/neu.0000000000002870
PMID:38412231
Abstract

The treatment of peripheral nerve injuries has seen tremendous innovations over the past century. Dr Gotthelf Carl Huber, an American immigrant and early experimental pioneer in the field of peripheral nerve injury, created a foundation of scientific knowledge for these advancements. At the beginning of his career, Huber published novel work in peripheral nerve injury, supporting the concept of Wallerian degeneration and demonstrating the use of nerve grafting for repair. As his scientific career evolved into other research areas at the University of Michigan, Huber's impact extended far beyond just the study of peripheral nerve injury. Because of the external forces of the First World War, Dr Huber's focus returned to translational projects concentrated on the treatment of neuromas and war time peripheral nerve injuries. Huber's scientific impact in the field of peripheral nerve injury and repair came as a result of his incredible work ethic, mentorship, and tremendous leadership qualities; through this, his work still influences clinical practice today, a century later.

摘要

在过去的一个世纪里,周围神经损伤的治疗取得了巨大的创新。戈特赫尔夫·卡尔·胡贝尔博士是一位美国移民,也是周围神经损伤领域早期的实验先驱,他为这些进展奠定了科学知识基础。在其职业生涯初期,胡贝尔发表了关于周围神经损伤的创新性研究成果,支持沃勒变性的概念,并展示了神经移植用于修复的方法。随着他的科研生涯在密歇根大学转向其他研究领域,胡贝尔的影响远远超出了周围神经损伤的研究范畴。由于第一次世界大战的外部因素,胡贝尔博士的重点又回到了专注于神经瘤治疗和战时周围神经损伤的转化项目上。胡贝尔在周围神经损伤和修复领域的科学影响力源于他令人难以置信的职业道德、指导能力和卓越的领导品质;正因如此,在一个世纪后的今天,他的工作仍然影响着临床实践。

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