Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115, USA.
Cell Rep Methods. 2024 Feb 26;4(2):100719. doi: 10.1016/j.crmeth.2024.100719.
In this issue of Cell Reports Methods, Parks et al. present an approach to non-invasively deliver adeno-associated viruses in a marmoset model using focused ultrasound (FUS) for neuronal tracing. The optimization of this technique in this non-human primate model is highly valuable for future FUS-mediated drug delivery studies.
在本期《细胞报告方法》中,Parks 等人提出了一种使用聚焦超声(FUS)在狨猴模型中进行非侵入性传递腺相关病毒用于神经元示踪的方法。该技术在这种非人类灵长类动物模型中的优化对于未来的 FUS 介导的药物递送研究具有非常重要的价值。