Chen Ying-Chun, Huang Hsing-Po
Botnar Research Centre, NDORMS, University of Oxford, Oxford, United Kingdom.
Department of Mechanical Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan.
Arthrosc Sports Med Rehabil. 2024 Jan 9;6(1):100842. doi: 10.1016/j.asmr.2023.100842. eCollection 2024 Feb.
To assess the potential of ultraviolet-visible near-infrared spectroscopy to provide quantitative information on the cartilage surface at early osteoarthritis.
We used a similar source and optical path to a standard arthroscope and constraining input to the range available to a standard detector/camera, further capturing and analyzing spectral information quantitatively in terms of specific electronic absorbance bands and scattering from the cartilage surface, with a focus on the early stages of degradation.
The ratio of the 320-nm and longer than 500-nm absorbances produced a distinct change from the normal to diseased states. The slopes between the wavelengths of 600 and 980 nm may show the transition of the single fibril to fibril bundles that occurs during early stages disease.
Ultraviolet-visible near-infrared spectroscopy has good potential for use in integrated arthroscopic assessment.
This raises the possibility of advancing arthroscopy from a qualitative to a quantitative tool, without requiring modification of either the radiation (the light source and path) or instrumentation (the arthroscope itself) delivered to the patient, thus allowing a low-cost yet potentially high-value technology.
评估紫外可见近红外光谱技术在早期骨关节炎中提供软骨表面定量信息的潜力。
我们使用了与标准关节镜类似的光源和光路，并将输入限制在标准探测器/摄像机可用的范围内，进一步根据特定的电子吸收带和软骨表面的散射对光谱信息进行定量采集和分析，重点关注早期退变阶段。
320纳米与大于500纳米吸光度的比值在从正常状态到患病状态时产生了明显变化。600至980纳米波长之间的斜率可能显示了疾病早期单纤维向纤维束的转变。
紫外可见近红外光谱技术在综合关节镜评估中具有良好的应用潜力。
这增加了将关节镜从定性工具提升为定量工具的可能性，而无需对输送给患者的辐射（光源和光路）或仪器（关节镜本身）进行修改，从而实现一种低成本但可能具有高价值的技术。
