Wassenaar E B, Van den Brand J G H
Department of General Surgery, University Medical Centre, Utrecht, The Netherlands.
J Clin Monit Comput. 2005 Jun;19(3):195-9. doi: 10.1007/s10877-005-1655-0.
Near-infrared spectroscopy (NIRS) is a promising non-invasive technique for the continuous monitoring of tissue oxygen delivery. NIRS detects light absorbance of haemoglobin chromophores to determine tissue oxygen saturation (StO2). As skin colour is also determined by the presence of chromophores, it is plausible that NIRS signal quality may be affected by dark skin pigmentation.
Tissue saturation in the anterior compartment of the lower leg during isometric contraction was measured using NIRS in 17 volunteers with dark skin pigmentation. Measurements were continued until StO2 was zero percent or until the signal disappeared.
The NIRS device failed to register tissue saturation values at some point in nine of seventeen volunteers. This occurred more often in individuals with darker skin.
In patients with a dark pigmented skin, NIRS StO2 measurements should be interpreted with caution, as melanin clearly interferes with the quality of the reflected NIRS signal.
近红外光谱技术（NIRS）是一种很有前景的用于连续监测组织氧输送的非侵入性技术。NIRS通过检测血红蛋白发色团的光吸收来测定组织氧饱和度（StO2）。由于肤色也由发色团的存在所决定，所以近红外光谱信号质量可能会受到深色皮肤色素沉着的影响，这是合理的推测。
在17名深色皮肤色素沉着的志愿者中，使用近红外光谱技术测量其小腿前侧等长收缩期间的组织饱和度。测量持续进行，直到StO2为零或信号消失。
在17名志愿者中，有9名在某些时候近红外光谱设备未能记录到组织饱和度值。这种情况在肤色较深的个体中更常出现。
对于深色皮肤色素沉着的患者，近红外光谱技术测量的StO2结果应谨慎解读，因为黑色素明显会干扰近红外光谱反射信号的质量。
