• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

[Pharmacokinetics and pharmacodynamics of 3-carbethoxyamino-5-dimethylamino-acetyl-iminodibenzyl hydrochloride (Bonnecor, AWD 19-166, GS 015) in the dog].

作者信息

Kaverina N V, Rodionov A P, Lyskovzev V V, Grigoreva J K, Sulakvelidze M T, Poppe H, Klemm W, Morgenroth U

出版信息

Pharmazie. 1985 Dec;40(12):869-70.

PMID:3841607
Abstract

The antiarrhythmic action of GS 015 was studied in proportion to its plasma concentrations ascertained in parallel, making use of the model of the two-step coronary ligature in the conscious dog. Blood levels of 1.0 microgram/ml (2 mg/kg i.v.) or of 0.8 microgram/ml (5 mg/kg orally) brought about a complete suppression of ectopic arrhythmias. The limit concentration for this effect is about 0.5 microgram/ml.

摘要

相似文献

1
[Pharmacokinetics and pharmacodynamics of 3-carbethoxyamino-5-dimethylamino-acetyl-iminodibenzyl hydrochloride (Bonnecor, AWD 19-166, GS 015) in the dog].
Pharmazie. 1985 Dec;40(12):869-70.
2
[Pharmacokinetics and pharmacodynamics of 3-carbethoxyamino-5-dimethylamino-acetyl-iminodibenzyl hydrochloride (Bonnecor, AWD 19-166, GS 015) in the cat].3-乙氧羰基氨基-5-二甲氨基-乙酰-亚氨基二苄基盐酸盐（Bonnecor，AWD 19-166，GS 015）在猫体内的药代动力学和药效学
Pharmazie. 1985 Dec;40(12):868-9.
3
[Antifibrillatory and anti-arrhythmic action of 3-carbethoxyamino-5-dimethylamino-acetyl iminodibenzyl hydrochloride (Bonnecor, AWD 19-166, GS 015) on models of myocardial ischemia].[3-乙氧羰基氨基-5-二甲氨基-乙酰亚氨基二苄基盐酸盐（邦尼可，AWD 19 - 166，GS 015）对心肌缺血模型的抗纤颤和抗心律失常作用]
Pharmazie. 1985 Dec;40(12):845-7.
4
[Circulatory action and adverse effects of 3-carbethoxyamino-5-dimethylamino-acetyl-iminodibenzyl hydrochloride (Bonnecor, AWD 19-166, GS 015) in the dog and cat].[3-乙氧羰基氨基-5-二甲基氨基-乙酰亚氨基二苄基盐酸盐（邦尼可，AWD 19 - 166，GS 015）对犬猫的循环作用及不良反应]
Pharmazie. 1985 Dec;40(12):857-61.
5
[Pharmacokinetics and metabolism of 3-carbethoxyamino-5-dimethylamino-acetyl-iminodibenzyl hydrochloride (Bonnecor, AWD 19-166, GS 015) in the rat].[3-乙氧羰基氨基-5-二甲氨基-乙酰-亚氨基二苄基盐酸盐（Bonnecor，AWD 19-166，GS 015）在大鼠体内的药代动力学与代谢]
Pharmazie. 1985 Dec;40(12):864-7.
6
[Antiarrhythmic action of 3-carbethoxyamino-5-dimethylaminoacetyl-iminodibenzyl hydrochloride (Bonnecor, AWD 19-166, GS -15) on experimental arrhythmia induced by aconitin, ouabain, calcium chloride and barium chloride].[盐酸3-乙氧羰基氨基-5-二甲氨基乙酰亚氨基二苄（邦尼可，AWD 19-166，GS-15）对乌头碱、哇巴因、氯化钙和氯化钡诱发的实验性心律失常的抗心律失常作用]
Pharmazie. 1985 Dec;40(12):836-40.
7
[Pharmacologic studies on the effect of 3-carbethoxyamino-5-dimethylamino-acetyl-iminodibenzyl hydrochloride (Bonnecor, AWD 19-166, GS 015) on the vegetative and central nervous system].[关于3-乙氧羰基氨基-5-二甲氨基-乙酰亚氨基二苄基盐酸盐（邦尼可，AWD 19-166，GS 015）对自主神经系统和中枢神经系统作用的药理学研究]
Pharmazie. 1985 Dec;40(12):875-8.
8
Electrophysiological effects of a new antiarrhythmic substance Bonnecor (AWD 19-166, GS 015) on mammalian myocardium.新型抗心律失常药物Bonnecor（AWD 19 - 166，GS 015）对哺乳动物心肌的电生理效应
Pharmazie. 1985 Dec;40(12):847-51.
9
[Characteristics of the anti-arrhythmic action of 3-carbethoxyamino-5-dimethylaminoacetyl-imino-dibenzyl hydrochloride (Bonnecor, AWD 19-166, GS 015)].[3-乙氧羰基氨基-5-二甲基氨基乙酰亚氨基二苄基盐酸盐（邦尼可，AWD 19-166，GS 015）的抗心律失常作用特征]
Pharmazie. 1985 Dec;40(12):840-4.
10
Inotropic effects of the antiarrhythmic compound Bonnecor (AWD 19-166, GS 015).抗心律失常化合物Bonnecor（AWD 19 - 166，GS 015）的变力作用
Pharmazie. 1985 Dec;40(12):854.