Lymphatic endothelial-like cells in the glioblastoma tumor niche drive metabolic alterations that promote stem cell proliferation and survival.
作者信息
Kidwell Reilly L, Aghi Manish K
机构信息
Department of Neurosurgery, University of California San Francisco, San Francisco, California, USA.
出版信息
Neuro Oncol. 2024 May 3;26(5):783-784. doi: 10.1093/neuonc/noae020.
Abstract
摘要
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Lymphatic endothelial-like cells promote glioblastoma stem cell growth through cytokine-driven cholesterol metabolism.淋巴内皮样细胞通过细胞因子驱动的胆固醇代谢促进神经胶质瘤干细胞生长。
Nat Cancer. 2024 Jan;5(1):147-166. doi: 10.1038/s43018-023-00658-0. Epub 2024 Jan 3.
2
Meningeal lymphatic vessels regulate brain tumor drainage and immunity.脑膜淋巴管调节脑肿瘤引流和免疫。
Cell Res. 2020 Mar;30(3):229-243. doi: 10.1038/s41422-020-0287-8. Epub 2020 Feb 24.
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IL-17A secreted from lymphatic endothelial cells promotes tumorigenesis by upregulation of PD-L1 in hepatoma stem cells.淋巴内皮细胞分泌的白细胞介素-17A 通过上调肝癌干细胞中的 PD-L1 促进肿瘤发生。
J Hepatol. 2019 Dec;71(6):1206-1215. doi: 10.1016/j.jhep.2019.08.034. Epub 2019 Sep 6.
4
Lymph Node Lymphatic Endothelial Cell Expansion and Contraction and the Programming of the Immune Response.淋巴结淋巴管内皮细胞的扩张和收缩与免疫反应的编程。
Front Immunol. 2019 Jan 25;10:36. doi: 10.3389/fimmu.2019.00036. eCollection 2019.
5
CNS lymphatic drainage and neuroinflammation are regulated by meningeal lymphatic vasculature.中枢神经系统的淋巴引流和神经炎症受脑膜淋巴血管调节。
Nat Neurosci. 2018 Oct;21(10):1380-1391. doi: 10.1038/s41593-018-0227-9. Epub 2018 Sep 17.
6
Tumor-associated Lymphatic Endothelial Cells Promote Lymphatic Metastasis By Highly Expressing and Secreting SEMA4C.肿瘤相关淋巴管内皮细胞通过高表达和分泌 SEMA4C 促进淋巴转移。
Clin Cancer Res. 2017 Jan 1;23(1):214-224. doi: 10.1158/1078-0432.CCR-16-0741. Epub 2016 Jul 8.
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CBTRUS Statistical Report: Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2008-2012.CBTRUS统计报告：2008 - 2012年美国原发性脑和中枢神经系统肿瘤诊断情况
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Structural and functional features of central nervous system lymphatic vessels.中枢神经系统淋巴管的结构和功能特征。
Nature. 2015 Jul 16;523(7560):337-41. doi: 10.1038/nature14432. Epub 2015 Jun 1.
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