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Diagnostics (Basel). 2023 Feb 17;13(4):760. doi: 10.3390/diagnostics13040760.
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The Fight against Infection and Pain: Devil's Claw () a Rich Source of Anti-Inflammatory Activity: 2011-2022.抗击感染和疼痛:南非钩麻是抗炎活性的丰富来源:2011-2022 年。
Molecules. 2022 Jun 6;27(11):3637. doi: 10.3390/molecules27113637.
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Global, regional prevalence, incidence and risk factors of knee osteoarthritis in population-based studies.基于人群研究的全球、地区膝关节骨关节炎的患病率、发病率及危险因素
EClinicalMedicine. 2020 Nov 26;29-30:100587. doi: 10.1016/j.eclinm.2020.100587. eCollection 2020 Dec.
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Injury prevention effects of stretching exercise intervention by physical therapists in male high school soccer players.物理治疗师对男性高中足球运动员进行拉伸运动干预的损伤预防效果。
Scand J Med Sci Sports. 2020 Nov;30(11):2178-2192. doi: 10.1111/sms.13777. Epub 2020 Aug 2.
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Projected Economic Burden of Periprosthetic Joint Infection of the Hip and Knee in the United States.美国人工髋关节和膝关节置换术后假体周围感染的预期经济负担。
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Health care resource utilization and burden of disease in a U.S. Medicare population with a principal diagnosis of osteoarthritis of the knee.美国医疗保险人群中膝关节骨关节炎主要诊断的医疗资源利用和疾病负担。
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八厘见健保健补充剂治疗有症状的膝骨关节炎的疗效。

Effectiveness of Bach Nien Kien Health Supplement in the Treatment of Patients With Symptomatic Knee Osteoarthritis.

机构信息

Department of Geriatrics, Hanoi Hospital of Traditional Medicine, Hanoi, Vietnam.

Inventive Medical Foundation, Department of Surgery, Keck School of Medicine of University of Southern California, Los Angeles, CA, U.S.A.

出版信息

In Vivo. 2024 Mar-Apr;38(2):963-970. doi: 10.21873/invivo.13528.

DOI:10.21873/invivo.13528
PMID:38418140
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10905488/
Abstract

BACKGROUND/AIM: Knee osteoarthritis (KOA) is the most common disease in adults. We conducted a clinical study to evaluate the efficacy and safety of Bach Nien Kien (BNK) in supportive therapy for patients with symptomatic KOA.

PATIENTS AND METHODS

An open interventional study was performed on 60 patients aged 38 to 70 with the diagnosis of symptomatic KOA. The patients were assigned to a study group (SG) with 30 subjects and a control group (CG) with 30 subjects using a matching method. The patients in SG were treated with electroacupuncture, glucosamine supplement, and BNK, while the patients in CG received the same treatment without BNK.

RESULTS

At the end of the 30-day treatment (d30), the SG had a reduction in VAS score compared to a pre-treatment level of 3.03±0.96 points, which was more than the CG of 2.5±0.90 points. The excellent result in the SG was 10%, and the CG had no excellent result. The good result in the SG was 56.7%, and the CG group was only 26.7%. The moderate and poor results in the CG were high, 63.3%, and 10%, respectively; in the SG, only 26.7% and 6.7%. The difference in overall treatment results between the SG and CG was statistically significant (p<0.05). During the 30-day treatment period in both groups, no patient reported any undesirable effects.

CONCLUSION

Bach Nien Kien health supplement is effective and safe for controlling KOA symptoms and improving joint motion and quality of life for patients with symptomatic KOA.

摘要

背景/目的:膝骨关节炎(KOA)是成年人中最常见的疾病。我们进行了一项临床研究,以评估 Bach Nien Kien(BNK)在治疗有症状的 KOA 患者中的疗效和安全性。

患者和方法

对 60 名年龄在 38 至 70 岁之间的有症状的 KOA 患者进行了一项开放的干预性研究。使用匹配方法将患者分为研究组(SG)和对照组(CG),每组 30 例。SG 患者接受电针、氨基葡萄糖补充剂和 BNK 治疗,而 CG 患者接受相同的治疗但不使用 BNK。

结果

在 30 天治疗结束时(d30),SG 的 VAS 评分与治疗前的 3.03±0.96 分相比降低了 3.03±0.96 分,而 CG 为 2.5±0.90 分。SG 的优秀结果为 10%,CG 无优秀结果。SG 的良好结果为 56.7%,CG 组仅为 26.7%。CG 组中度和差的结果较高,分别为 63.3%和 10%;而 SG 组仅为 26.7%和 6.7%。SG 和 CG 之间的总体治疗结果差异具有统计学意义(p<0.05)。在两组的 30 天治疗期间,没有患者报告任何不良反应。

结论

Bach Nien Kien 健康补充剂对于控制 KOA 症状、改善关节运动和提高有症状的 KOA 患者的生活质量是有效和安全的。