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比较不同分级膝关节骨关节炎电针治疗的有效性:一项前瞻性研究。

Comparing the Effectiveness of Electroacupuncture with Different Grades of Knee Osteoarthritis: A Prospective Study.

作者信息

Qi Li, Tang Yonggang, You Yong, Qin Fengling, Zhai Lijuan, Peng Hongxia, Nie Rongrong

机构信息

Department of Neurological Rehabilitation, 181st Central Hospital of The Chinese People's Liberation Army, Guilin, Guangxi, China.

出版信息

Cell Physiol Biochem. 2016;39(6):2331-2340. doi: 10.1159/000447925. Epub 2016 Nov 11.

Abstract

BACKGROUND

The electroacupuncture (EA) with different number of points significantly affected its efficacy on knee osteoarthritis (KOA), and the severity of KOA also influenced its response to treatments. Hence, we prospectively compared the clinical efficacy of EA on KOA with different severities.

METHODS

A total of 132 KOA patients recruited from 181st Central Hospital of The Chinese People's Liberation Army between March 2014 and March 2015 were classified into 4 KOA stages according to Kellgren Lawrence grading scale. They were allocated into three treatment groups, including two-point group, four-point group and six-point group. Patients in the six-point group received treatment at six-points including ST34, SP10, SP9, ST36, ST35 and EX-LE4. Patients in the four-point group received treatment at ST34, SP10, ST35 and EX-LE5, while patients in the two-point group received treatment at ST35 and EX-LE4. Visual Analog Scale (VAS), McMaster Universities Osteoarthritis Index (WOMAC) and self-assessment questionnaire of patients were assessed after treatment.

RESULTS

Three kinds of EA treatments all have significant clinical effects on KOA patients with down-regulated scores of VAS and WOMAC. Regarding post-treatment efficacy, the six point group exhibited lower VAS score and higher WOMAC score compared with the other two groups. For patients with different KOA grades, patients with higher KOA grades were associated with lower grade of treatment efficacy.

CONCLUSIONS

Patients with KOA, especially those with lower KOA stages, could gain beneficial efficacies from EA treatments with two, four and six points, respectively.

摘要

背景

不同穴位数量的电针(EA)对膝骨关节炎(KOA)的疗效有显著影响,且KOA的严重程度也会影响其对治疗的反应。因此,我们前瞻性地比较了不同严重程度的KOA患者接受电针治疗的临床疗效。

方法

2014年3月至2015年3月期间从中国人民解放军第181中心医院招募的132例KOA患者,根据Kellgren Lawrence分级量表分为4个KOA阶段。他们被分为三个治疗组,包括两点组、四点组和六点组。六点组患者在六个穴位接受治疗,包括ST34、SP10、SP9、ST36、ST35和EX-LE4。四点组患者在ST34、SP10、ST35和EX-LE5接受治疗,而两点组患者在ST35和EX-LE4接受治疗。治疗后评估视觉模拟量表(VAS)、麦马斯特大学骨关节炎指数(WOMAC)和患者自我评估问卷。

结果

三种电针治疗方法对KOA患者均有显著临床效果,VAS和WOMAC评分均下调。关于治疗后疗效,六点组与其他两组相比,VAS评分更低,WOMAC评分更高。对于不同KOA等级的患者,KOA等级越高,治疗效果等级越低。

结论

KOA患者,尤其是KOA分期较低者,分别接受两点、四点和六点的电针治疗均可获得有益疗效。

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