Department of Juridical and Economic Studies, Sapienza University of Rome, P.le A. Moro 5, 00185, Rome, Italy.
Department of Humanistic and International Social Sciences, UNINT University for International Studies, Via C. Colombo, 200, 00147, Rome, Italy.
Sci Rep. 2024 Feb 28;14(1):4901. doi: 10.1038/s41598-024-54989-8.
Patients with Type 2 Diabetes Mellitus (T2DM) are rapidly increasing in Italy due to aging, preventable risk factors, and worsening socioeconomic context. T2DM and its sequelae take a heavy toll on healthcare systems and the economy, given costly management, difficulties in coping with everyday life, and decreasing patient/worker productivity. Considering long life expectancy in Italy and a decreasing mortality rate due to T2DM, this study aims to calculate the years lived with disability (YLDs) of T2DM and its sequelae grouped into three categories: Neuropathy, Chronic Kidney Disease and No Complications, taking into consideration sex, year, and geographical location. This is the first attempt to measure YLDs from data that do not rely on self-reported diabetes diagnoses. Data come from the Italian Diabetologists Association dataset, the most comprehensive longitudinal source of national outpatient data. YLDs are obtained by multiplying the number of individuals living with a specific health condition and a disability weight which represents the magnitude of health loss associated with that particular condition. Findings show increasing YLD age-standardized rates for T2DM and its sequelae, especially Neuropathy, with the trend being stronger in the central macro-region and among men, and that 2009 marks a structural change in YLD growth rate. Systematic data collection for measuring the burden of diseases is key, among other things, to policy-making and implementation.
意大利的 2 型糖尿病(T2DM)患者数量迅速增加,这是由于人口老龄化、可预防的风险因素以及不断恶化的社会经济环境所致。T2DM 及其并发症给医疗保健系统和经济带来了沉重的负担,因为其管理费用高昂、日常生活应对困难以及患者/工人的生产力下降。考虑到意大利人的预期寿命较长,以及由于 T2DM 导致的死亡率下降,本研究旨在计算 T2DM 及其并发症的残疾生命年(YLDs),将其分为三类:神经病变、慢性肾脏病和无并发症,并考虑到性别、年份和地理位置。这是首次尝试从不依赖于自我报告的糖尿病诊断数据来衡量 YLDs。数据来自意大利糖尿病学家协会数据集,这是全国门诊数据最全面的纵向来源。YLDs 通过将患有特定健康状况和残疾权重的个体数量相乘来获得,残疾权重代表与特定状况相关的健康损失程度。研究结果表明,T2DM 及其并发症的 YLD 年龄标准化率不断上升,尤其是神经病变,在中部大区和男性中这一趋势更为明显,2009 年标志着 YLD 增长率的结构性变化。除其他事项外,系统地收集疾病负担数据是制定和实施政策的关键。