两例婴儿在接受麻疹、腮腺炎和风疹（MMR）疫苗接种后，由于肠道派尔集合淋巴结异常增生导致肠套叠引起的小肠坏死。
Two cases of small bowel necrosis due to intussusception secondary to abnormal proliferation of intestinal Peyer's patches in infants after MMR vaccination.
机构信息
Xi'an International Medical Center Hospital Affiliated to Northwest University, No.777 Xitai Road, Chang'an District, Xi'an City, Shaanxi Province, China.
The Affiliated Hospital of Northwest University/Xi'an No.3 Hospital, No. 10 East Section of Fengcheng 3rd Road, Weiyang District, Xi'an , China.
出版信息
BMC Pediatr. 2024 Feb 29;24(1):147. doi: 10.1186/s12887-024-04618-0.
BACKGROUND
Intussusception is one of the most common acute abdominal conditions in pediatric patients, and if left untreated, it may result in intestinal necrosis and even death. The etiology of the disease is unknown and may be related to a variety of factors, and there are only limited reports of small bowel necrosis secondary to abnormal Peyer's node hyperplasia after MMR vaccination.
CASE PRESENTATION
In this report, we present two infants who had an abnormal proliferation of Peyer's nodes secondary to intussusception eventually leading to small bowel necrosis after MMR vaccination.
CONCLUSIONS
Intestinal necrosis and infectious shock are the most common causes of infant mortality, and early detection and management are critical.
背景
肠套叠是小儿患者最常见的急性腹部病症之一，如果不加以治疗，可能会导致肠坏死，甚至死亡。该疾病的病因尚不清楚，可能与多种因素有关，且仅有少数关于 MMR 疫苗接种后异常派尔集合淋巴结增生导致小肠坏死的报道。
病例介绍
本报告介绍了两名婴儿，他们在 MMR 疫苗接种后因肠套叠导致派尔集合淋巴结异常增生，最终导致小肠坏死。
结论
肠坏死和感染性休克是婴儿死亡的最常见原因，早期发现和管理至关重要。
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