Wolf I H, Kanitz W
Uremia Invest. 1985;9(2):181-6. doi: 10.3109/08860228509088209.
A method of [123I]hippuran (OIH) renogram evaluation is proposed, which delivers transition rates for total and split renal clearance. It is based on the reconstruction of the true kidney input, using an equation of balance and a two-compartment model assumption of OIH kinetics. Results are compared with clearance determinations using whole body principles and transit time determination by deconvolution. It is shown that the reconstructed true input corresponds to the plasma activity while the vascular volume of distribution corresponds to the blood.
提出了一种[123I]马尿酸(OIH)肾图评估方法,该方法可得出总肾清除率和分肾清除率的转换率。它基于真实肾脏输入的重建,使用平衡方程和OIH动力学的二室模型假设。将结果与使用全身原理的清除率测定以及通过反卷积确定的通过时间进行比较。结果表明,重建的真实输入对应于血浆活性,而血管分布容积对应于血液。