Institute of Primary Care, University of Zurich and University Hospital Zürich, Pestalozzistrasse 24, 8091, Zurich, Switzerland.
mediX Ticino and Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese Moncucco, Lugano, Switzerland.
Sci Rep. 2024 Feb 29;14(1):4978. doi: 10.1038/s41598-024-55166-7.
Patient information leaflets can reduce antibiotic prescription rates by improving knowledge and encouraging shared decision making (SDM) in patients with respiratory tract infections (RTI). The effect of these interventions in antibiotic low-prescriber settings is unknown. We conducted a pragmatic pre-/post interventional study between October 2022 and March 2023 in Swiss outpatient care. The intervention was the provision of patient leaflets informing about RTIs and antibiotics use. Main outcomes were the extent of SDM, antibiotic prescription rates, and patients' awareness/knowledge about antibiotic use in RTIs. 408 patients participated in the pre-intervention period, and 315 patients in the post- intervention period. There was no difference in the extent of SDM (mean score (range 0-100): 65.86 vs. 64.65, p = 0.565), nor in antibiotic prescription rates (no prescription: 89.8% vs. 87.2%, p = 0.465) between the periods. Overall awareness/knowledge among patients with RTI was high and leaflets showed only a small effect on overall awareness/knowledge. In conclusion, in an antibiotic low-prescriber setting, patient information leaflets may improve knowledge, but may not affect treatment decisions nor antibiotic prescription rates for RTIs.
患者信息手册可以通过提高知识水平并鼓励呼吸道感染 (RTI) 患者共同决策 (SDM)，从而降低抗生素处方率。这些干预措施在抗生素低处方环境中的效果尚不清楚。我们在 2022 年 10 月至 2023 年 3 月期间在瑞士门诊护理中进行了一项实用的预/后干预研究。干预措施是提供有关 RTI 和抗生素使用的患者手册。主要结果是 SDM 的程度、抗生素处方率以及患者对 RTI 中抗生素使用的认识/知识。408 名患者参加了干预前阶段，315 名患者参加了干预后阶段。SDM 的程度（平均得分（范围 0-100）：65.86 与 64.65，p=0.565）和抗生素处方率（无处方：89.8%与 87.2%，p=0.465）在两个阶段之间没有差异。总体而言，RTI 患者的整体认识/知识水平较高，手册对整体认识/知识的影响较小。总之，在抗生素低处方环境中，患者信息手册可能会提高知识水平，但可能不会影响治疗决策或 RTI 的抗生素处方率。
