Ren Wenfei, Li Jiguang, Zu Baiyi, Lei Da, Dou Xincun
Xinjiang Key Laboratory of Trace Chemicals Sensing, Xinjiang Technical Institute of Physics & Chemistry, Chinese Academy of Sciences, Urumqi 830011, China.
Center of Materials Science and Optoelectronics Engineering, University of Chinese Academy of Sciences, Beijing 100049, China.
JACS Au. 2024 Jan 23;4(2):545-556. doi: 10.1021/jacsau.3c00667. eCollection 2024 Feb 26.
The exploration of emerging functionalized quantum dots (QDs) through modulating the effective interaction between the sensing element and target analyte is of great significance for high-performance trace sensing. Here, the chromone-based ligand grafted QDs (QDs-Chromone) were initiated to realize the electronic energy transfer (EET) driven specifically by ethylenediamine (EDA) in the absence of spectral overlap. The fluorescent and colorimetric dual-mode responses (from red to blue and from colorless to yellow, respectively) resulting from the expanded conjugated ligands reinforced the analytical selectivity, endowing an ultrasensitive and specific response to submicromolar-liquid of EDA. In addition, a QDs-Chromone-based sensing chip was constructed to achieve the ultrasensitive recognition of EDA vapor with a naked-eye observed response at a concentration as low as 10 ppm, as well as a robust anti-interfering ability in complicated scenarios monitoring. We expect the proposed EET strategy in shaping functionalized QDs for high-performance sensing will shine light on both rational probe design methodology and deep sensing mechanism exploration.
通过调节传感元件与目标分析物之间的有效相互作用来探索新兴的功能化量子点（QDs）对于高性能痕量传感具有重要意义。在此，引发了基于色酮的配体接枝量子点（QDs-色酮），以在不存在光谱重叠的情况下实现由乙二胺（EDA）特异性驱动的电子能量转移（EET）。扩展的共轭配体产生的荧光和比色双模式响应（分别从红色变为蓝色和从无色变为黄色）增强了分析选择性，赋予了对亚微摩尔浓度EDA液体的超灵敏和特异性响应。此外，构建了基于QDs-色酮的传感芯片，以实现对EDA蒸气的超灵敏识别，在低至10 ppm的浓度下有肉眼可见的响应，以及在复杂场景监测中具有强大的抗干扰能力。我们期望所提出的用于塑造高性能传感功能化量子点的EET策略将为合理的探针设计方法和深入的传感机制探索提供启示。
