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下肢肌肉力量作为减重手术后的预测指标。

Muscle Strength of Lower Limbs as a Postoperative Predictor in Bariatric Surgery.

机构信息

Gastroenterology Department, University of São Paulo Medical School, Brazil.

Orthopedics and Traumatology Department, University of São Paulo Medical School, Brazil.

出版信息

J Musculoskelet Neuronal Interact. 2024 Mar 1;24(1):31-37.

PMID:38427366
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10910205/
Abstract

OBJECTIVE

The aim of our study was to assess postoperative lower limbs muscle strength (MS) as a predictor of late surgical success (36 months).

METHODS

Body composition analyses and isokinetic dynamometry evaluation were performed before (T0: n=123), six months (T1: n=123) and 36 months (T2: n=79) after Roux-en-y gastric bypass (RYGB). Surgical success (SS) was defined as ≥ 50% excess weight loss (EWL) 36 months after surgery or ≤ 50% surgical failure (SF).

RESULTS

There was no difference between relative MS extension (Ext) and flexion (Flex) in T1 and T2. There was also, no difference between relative MS Ext and Flex in T1 and T2 between patients with SS and SF. There was a difference in relative MS Ext (144.9 ± 39.8 Nm/kg x 125.5 ± 29.2 Nm/kg; p=0.04) and Flex (73.6 ± 21.8 Nm/kg x 60.4 ± 15.8 Nm/kg; p=0.02) between SS and SF patients only in T2. Patients with an increment in Ext and Flex MS ≥4 Nm/kg at T1 had approximately 76% of SS at 36 months.

CONCLUSION

An increase of lower limbs MS ≥4 Nm/kg 6 months after RYGB predicts SS at 36 months.

CLINICALTRIALS

gov ID: NCT04129801.

摘要

目的

我们研究的目的是评估术后下肢肌肉力量(MS)作为预测晚期手术成功(36 个月)的指标。

方法

在 Roux-en-y 胃旁路术(RYGB)前(T0:n=123)、术后 6 个月(T1:n=123)和 36 个月(T2:n=79)进行身体成分分析和等速测力评估。手术成功(SS)定义为手术后 36 个月体重减轻≥50%(EWL)或≤50%手术失败(SF)。

结果

T1 和 T2 时,相对伸肌(Ext)和屈肌(Flex)的 MS 无差异。SS 和 SF 患者 T1 和 T2 时,相对伸肌和 Flex 的 MS 也无差异。仅在 T2 时,SS 和 SF 患者的相对伸肌 Ext(144.9±39.8 Nm/kg 对 125.5±29.2 Nm/kg;p=0.04)和 Flex(73.6±21.8 Nm/kg 对 60.4±15.8 Nm/kg;p=0.02)有差异。T1 时 MS Ext 和 Flex 增加≥4 Nm/kg 的患者,36 个月时 SS 约为 76%。

结论

RYGB 后 6 个月下肢 MS 增加≥4 Nm/kg 可预测 36 个月时的 SS。

临床试验

gov ID:NCT04129801。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4d/10910205/9aee6de737a0/JMNI-24-031-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4d/10910205/3b6a71e99a71/JMNI-24-031-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4d/10910205/9aee6de737a0/JMNI-24-031-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4d/10910205/3b6a71e99a71/JMNI-24-031-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6d4d/10910205/9aee6de737a0/JMNI-24-031-g002.jpg

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