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[Dipyridamole as an inhibitor of vaccinia virus replication].

作者信息

Korbecki M, Bankowski A, Filczak K, Klimek A

出版信息

Mol Gen Mikrobiol Virusol. 1985 Jan(1):29-32.

PMID:3842738
Abstract

Dipyridamole in concentration of 25 microM inhibited the multiplication of vaccinia virus in about 90% of cells. In the presence of this substance, [3H]-uptake was sharply reduced both in uninfected and infected RK13 cells, while [14C]-uptake was not inhibited incorporation of [3H]-thymidine and [14C]-amino acids into viral particles. The present findings suggest that the antiviral character of dipyridamole is related with the inhibition of the substrate transport through the cell membrane.

摘要

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