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赞比亚非传染性疾病及其相关风险因素导致的死亡率;2015/2016 年样本生命登记与死因推断分析。

Mortality from non-communicable diseases and associated risk factors in Zambia; analysis of the sample vital registration with verbal autopsy 2015/2016.

机构信息

Department of Population Studies, School of Humanities and Social Sciences, University of Zambia, Lusaka, Zambia.

出版信息

BMC Public Health. 2024 Mar 1;24(1):666. doi: 10.1186/s12889-024-18150-4.

Abstract

BACKGROUND

Non-communicable diseases (NCDs) are the world's growing cause of preventable illness, disability, morbidity, and mortality which account for 71% of deaths. The aim of this study was to determine the factors associated with mortality from NCDs among persons aged 15 years and above in Zambia.

METHODOLOGY

The study used data from Sample Vital Registration with Verbal Autopsy (SAVVY) 2015/16 (Zambia). A total of 3529 Verbal Autopsy were completed in the study, with only 2599 of death where among people aged 15 years and above. Three-level data analysis was applied; univariate analysis, bivariate analysis, and multivariate analysis (binary logistic regression).

FINDINGS

The overall number of deaths from NCDs was 28.81%. Stratified analysis by gender showed that deaths from NCDs were higher among women (32.60%) as compared to men (26.25%). Among all persons, dying from NCDs was associated with tobacco use, age, and education. Tobacco use was negatively associated with mortality from NCDs (adjusted odds ratio [aOR] = 0.68; 95% confidence interval [CI]: 0.48-0.98). Age was positively associated with the odds of dying from NCDs among persons aged 45-59 years (aOR = 3.87, 95% CI: 2.13-7.01), 60-74 years (aOR = 12.05, 95% CI: 6.44-22.55), and 75 + years (aOR = 15.16, 95% CI: 7.93-28.97). The likelihood of dying from NCDs was higher among persons with secondary education as compared to those with no education (aOR = 1.93, 95% CI: 1.11-3.33).

CONCLUSION

The findings from this study suggest that public health interventions targeting NCDs need to consider behavioural factors, especially tobacco use which exposes people to second-hand smoke. We also recommend large-scale national-level studies to further examine the contribution of each factor leading to mortality from NCDs.

摘要

背景

非传染性疾病(NCDs)是世界范围内可预防疾病、残疾、发病和死亡的主要原因,占死亡人数的 71%。本研究旨在确定赞比亚 15 岁及以上人群中与 NCD 相关的死亡因素。

方法

本研究使用了 2015/16 年样本生命登记与死因推断(SAVVY)的数据。该研究共完成了 3529 次死因推断,其中只有 2599 人死亡年龄在 15 岁及以上。采用三级数据分析;单变量分析、双变量分析和多变量分析(二元逻辑回归)。

结果

NCD 总死亡人数为 28.81%。按性别分层分析显示,女性(32.60%)死于 NCD 的人数高于男性(26.25%)。在所有人群中,死于 NCD 与烟草使用、年龄和教育有关。烟草使用与 NCD 死亡率呈负相关(调整后的优势比[aOR] = 0.68;95%置信区间[CI]:0.48-0.98)。年龄与 45-59 岁(aOR = 3.87,95% CI:2.13-7.01)、60-74 岁(aOR = 12.05,95% CI:6.44-22.55)和 75 岁及以上(aOR = 15.16,95% CI:7.93-28.97)人群中死于 NCD 的几率呈正相关。与没有受过教育的人相比,具有中等教育程度的人死于 NCD 的可能性更高(aOR = 1.93,95% CI:1.11-3.33)。

结论

本研究结果表明,针对 NCD 的公共卫生干预措施需要考虑行为因素,特别是使人们接触二手烟的烟草使用。我们还建议进行大规模的国家级研究,以进一步研究导致 NCD 死亡率的每个因素的贡献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/190d/10908156/26f63e68cdd3/12889_2024_18150_Fig1_HTML.jpg

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