Kim Han-Seul, Myeong So Yeon, Kang Hee Young, Kim Jin Cheol
Department of Dermatology, Ajou University School of Medicine, Suwon, South Korea.
Department of Biomedical Sciences, Molecular Medicine, Graduate School of Ajou University, Suwon, South Korea.
Sci Rep. 2024 Mar 4;14(1):5223. doi: 10.1038/s41598-024-55617-1.
Seborrheic keratosis (SK) is a common skin disease in the elderly. However, in cases where SK presenting as multiple skin-colored or clustered lesions can be easily misdiagnosed as verruca plana (VP), especially in the young population. This retrospective study investigated the prevalence of SK and VP in the lesions that appear clinically similar to VP according to age. We examined the pathology slides of the skin tissue and photographs of patients who were clinically suspected to have VP. A total of 503 patients were included in the study, out of which 174 patients were finally diagnosed with SK (34.6%) and 132 with VP (26.2%). The mean ages of the SK- and VP-diagnosed group were 39.3 and 35.4 years, respectively. SK had a higher prevalence among individuals older than 30 years, and relative frequency of SK should not be ignored in patients with a grouped distribution in their 20 s and 30 s. Therefore, our study suggests that multiple verrucous skin-colored to brownish plaques are also commonly diagnosed as SK in young people as well as VP, and the prevalence of SK and VP may not always depend solely on chronological aging, and the prevalence of SK among young people may be higher than commonly believed stereotypes suggest.
脂溢性角化病（SK）是老年人常见的皮肤病。然而，当SK表现为多发性肤色或簇状损害时，很容易被误诊为扁平疣（VP），尤其是在年轻人群中。这项回顾性研究根据年龄调查了临床上与VP相似的损害中SK和VP的患病率。我们检查了临床疑似患有VP的患者的皮肤组织病理切片和照片。共有503例患者纳入研究，其中174例最终诊断为SK（34.6%），132例诊断为VP（26.2%）。SK诊断组和VP诊断组的平均年龄分别为39.3岁和35.4岁。SK在30岁以上人群中患病率较高，20多岁和30多岁呈群集分布的患者中SK的相对频率也不应被忽视。因此，我们的研究表明，多发性疣状肤色至褐色斑块在年轻人中通常被诊断为SK以及VP，SK和VP的患病率可能并不总是仅取决于年龄增长，年轻人中SK的患病率可能高于普遍认知。
