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在东南亚地区建立和维护用于高致病性兽医和“同一健康”病原体的生物样本库的重要性与挑战

The Importance and Challenges of Implementing and Maintaining Biorepositories for High-Consequence Veterinary and One Health Pathogens in South-East Asia.

作者信息

Oyuchua Malinee, Siengsanan-Lamont Jarunee, Le Kim Khanh, Kamolsiripichaiporn Somjai, Areerob Jeeranan, Thongkamkoon Pacharee, Theppangna Watthana, Phommachanh Phouvong, Tum Sothyra, Johnson Barbara, Blacksell Stuart D

机构信息

Mahidol-Oxford Tropical Research Medicine Unit, Faculty of Tropical Medicine, Mahidol University, Bangkok, Thailand.

National Institute of Animal Health, Department of Livestock Development, Bangkok, Thailand.

出版信息

Appl Biosaf. 2024 Mar 1;29(1):35-44. doi: 10.1089/apb.2023.0006. Epub 2024 Feb 28.

Abstract

INTRODUCTION

Emerging infectious diseases pose a threat to public health and the economy, especially in developing countries. Southeast Asian veterinary laboratories handle numerous high-risk pathogens, making pathogen accountability crucial for safe handling and storage.

METHODS

Thirteen veterinary laboratories in Cambodia ( = 1), Lao People's Democratic Republic ( = 1), and Thailand ( = 11) participated in a study conducted between 2019 and 2020. Data were collected using a questionnaire, group discussions, and interviews.

CONCLUSION

Significant gaps in biosecurity and biorepository management were recognized and discussed in the context of regional biosafety and biosecurity. Laboratories could use the findings and recommendations of the study to develop or improve their pathogen inventory and biosecurity systems. Governments play a significant role in setting standards and regulations and providing necessary support for laboratories to maintain inventory controls sustainably and have a very important role to play in ensuring biosafety and biosecurity compliance.

摘要

引言

新发传染病对公共卫生和经济构成威胁,在发展中国家尤为如此。东南亚兽医实验室处理大量高风险病原体,因此病原体问责制对于安全处理和储存至关重要。

方法

柬埔寨(=1)、老挝人民民主共和国(=1)和泰国(=11)的13个兽医实验室参与了2019年至2020年期间开展的一项研究。通过问卷调查、小组讨论和访谈收集数据。

结论

在区域生物安全和生物安保背景下,认识到并讨论了生物安全和生物样本库管理方面的重大差距。实验室可利用该研究的结果和建议来制定或改进其病原体清单和生物安全系统。政府在制定标准和法规以及为实验室提供必要支持以可持续地维持库存控制方面发挥着重要作用,并且在确保生物安全和生物安保合规方面发挥着非常重要的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3c1d/10902268/06d7ca334012/apb.2023.0006_figure1.jpg

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