Brizee Sabrina, van Passel Mark W J, van den Berg Linda M, Feakes Daniel, Izar Ana, Lin Kathryn Tham Bee, Podin Yuwana, Yunus Zalini, Bleijs Diederik A
National Institute for Public Health and the Environment (RIVM), Bilthoven, the Netherlands.
Biological Weapons Convention Implementation Support Unit, United Nations Office for Disarmament Affairs, Palais des Nations, Geneva, Switzerland.
Appl Biosaf. 2019 Jun;24(2):83-89. doi: 10.1177/1535676019838077. Epub 2019 Mar 27.
Laboratory biosecurity is of continuously growing interest due to increasing concerns about deliberate misuse of biological materials and emerging biological risks. These risks continue to be magnified by globalization, the rapid pace of scientific development, and dual-use technologies. Worldwide laboratory capacities are expanding, which calls for concrete actions to improve laboratory biosafety and biosecurity practices to protect researchers and the community. Hence, laboratories require comprehensive biorisk management programs to minimize the risk of accidental and deliberate release of infectious biological materials.
Malaysia has prioritized the concern of national biosecurity and aims to consolidate laboratory biosecurity performance to detect and prevent the deliberate release of biological agents.
Two 3-day workshops were organized over the course of four months in which Malaysia collaborated with The Netherlands. This bilateral engagement aimed to integrate biosecurity practices in their national biorisk management programs, and resulted into a comprehensive biosecurity checklist for laboratory assessment and monitoring.
This biosecurity checklist is based on Malaysian and Dutch expert opinions and national and international guidelines and regulations. The biosecurity checklist is a survey-driven tool that consists of a set of concrete questions for each key biosecurity area, which are discussion points for assessment.
We display a practical biosecurity checklist for laboratory assessment and monitoring. Although the presented checklist was the template for the specific Malaysia checklist, it could serve as a template for other countries.
由于对生物材料的蓄意滥用和新出现的生物风险的担忧日益增加，实验室生物安全受到越来越多的关注。全球化、科学发展的快速步伐和两用技术继续放大这些风险。全球实验室能力正在扩大，这就需要采取具体行动来改善实验室生物安全和生物安保措施，以保护研究人员和社区。因此，实验室需要全面的生物风险管理计划，以尽量减少传染性生物材料意外和蓄意释放的风险。
马来西亚已将国家生物安全问题列为优先事项，旨在巩固实验室生物安保绩效，以检测和防止生物制剂的蓄意释放。
在四个月的时间里组织了两次为期三天的研讨会，马来西亚与荷兰在研讨会上进行了合作。这种双边合作旨在将生物安保措施纳入其国家生物风险管理计划，并形成了一份用于实验室评估和监测的全面生物安保清单。
这份生物安保清单基于马来西亚和荷兰专家的意见以及国家和国际准则与法规。该生物安保清单是一种基于调查的工具，由针对每个关键生物安保领域的一系列具体问题组成，这些问题是评估的讨论要点。
我们展示了一份用于实验室评估和监测的实用生物安保清单。尽管所展示的清单是马来西亚特定清单 的模板，但它也可以作为其他国家的模板。
