Shaw Tania
Surgery Department, Animal Referral Hospital Melbourne, 72 Hargrave Avenue, Essendon Fields, VIC 3041, Australia.
Can Vet J. 2024 Mar;65(3):241-244.
Carcinoids are rare tumors that originate from neuroendocrine system cells. There has apparently only been 1 report in the veterinary medical literature of a cat with a gallbladder carcinoid, with no long-term follow-up information available from that case. Furthermore, apparently only 9 dogs with gallbladder carcinoids have been reported, again with no long-term follow-up. This case report describes the clinical presentation, surgical appearance, histopathologic and immunohistochemical findings, postoperative adjuvant chemotherapy treatment, and long-term outcome of a domestic longhair cat with a gallbladder carcinoid. The diagnosis of a gallbladder carcinoid in the present case was based on histologic and immunohistochemical findings. Clinical signs of a gallbladder carcinoid are nonspecific and ultrasonographic findings may not be definitive; however, it should be considered as a potential differential diagnosis in cats with lesions of the gallbladder or in the region of the gallbladder. The prognosis is poor, with a potentially high metastatic rate. In the present case, metastasis occurred 7 mo postoperatively despite adjuvant therapy, and the survival time was only 10 mo from the time of diagnosis. Key clinical message: This case report describes the clinical presentation, surgical appearance, histopathologic and immunohistochemical findings, postoperative adjuvant treatment, and long-term outcome of a cat with a gallbladder carcinoid, which should be considered as a potential differential diagnosis in cats with lesions of the gallbladder or in the region of the gallbladder.
类癌是起源于神经内分泌系统细胞的罕见肿瘤。兽医医学文献中显然仅有1例关于猫胆囊类癌的报道,且该病例没有长期随访信息。此外,显然仅有9例犬胆囊类癌的报道,同样也没有长期随访。本病例报告描述了一只家养长毛猫胆囊类癌的临床表现、手术外观、组织病理学和免疫组化结果、术后辅助化疗治疗以及长期预后。本病例中胆囊类癌的诊断基于组织学和免疫组化结果。胆囊类癌的临床症状不具有特异性,超声检查结果可能也不明确;然而,对于胆囊或胆囊区域有病变的猫,应将其视为一种潜在的鉴别诊断。预后较差,转移率可能较高。在本病例中,尽管进行了辅助治疗,但术后7个月仍发生了转移,从诊断时起存活时间仅为10个月。关键临床信息:本病例报告描述了一只猫胆囊类癌的临床表现、手术外观、组织病理学和免疫组化结果、术后辅助治疗以及长期预后,对于胆囊或胆囊区域有病变的猫,应将其视为一种潜在的鉴别诊断。