Esfandiari Zahra, Shoaei Parisa, Vakili Bahareh, Farajzadegan Ziba, Tarrahi Mohammad Javad, Emami Zahra, Fakhri Yadolah, Weese J Scott, Mahmudiono Trias
Nutrition and Food Security Research Center, Department of Food Science and Technology, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran.
Nosocomial Infection Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Iran J Public Health. 2023 Dec;52(12):2516-2527. doi: 10.18502/ijph.v52i12.14313.
Meat and meat products are introduced as one of the frequent sources of . We aimed to determine the prevalence and antibiotic resistance of isolates in meat and meat products using a systematic review and meta-analysis.
A literature search was performed in the primary international and bibliographic databases such as MEDLINE (PubMed), Cochrane Library, Embase, Scopus, and Web of Science to achieve all articles related to the prevalence and antibiotic resistance rates from 2007 to 2022.
The 278 retrieved articles were reduced to 54 worldwide eligible studies after screening and matching inclusion/exclusion criteria. was examined in different types of samples and its resistance to 10 antibiotics. The pooled prevalence of was 3.4% in all samples. pooled prevalence was detected in fish, poultry, and red meat groups with 6.9%, 5.2%, and 3.2%, respectively. Regarding antibiotic resistance, the highest pooled prevalence was for ciprofloxacin (86.6%), followed by clindamycin (42.6%) and erythromycin (34%). The lowest pooled prevalence was observed in metronidazole (7.6%), vancomycin (6.6%), and chloramphenicol (6%).
Low resistance was found to commonly used drugs for infection (CDI) treatment. Since each antibiotic can be predisposing cause for CDI development, this finding possibly will be warning from a One Health viewpoint about the misuse of antibiotics in the chain of farm to fork including agriculture, animal husbandry and the food industry and also their injudicious use in medicine.
肉类和肉制品被认为是常见的[病原体名称]来源之一。我们旨在通过系统评价和荟萃分析来确定肉类和肉制品中[病原体名称]分离株的流行率和抗生素耐药性。
在主要的国际和文献数据库（如MEDLINE（PubMed）、Cochrane图书馆、Embase、Scopus和Web of Science）中进行文献检索，以获取2007年至2022年期间所有与流行率和抗生素耐药率相关的文章。
经过筛选和匹配纳入/排除标准后，检索到的278篇文章减少到全球范围内54项符合条件的研究。在不同类型的样本中检测了[病原体名称]及其对10种抗生素的耐药性。所有样本中[病原体名称]的合并流行率为3.4%。在鱼类、家禽和红肉组中分别检测到合并流行率为6.9%、5.2%和3.2%。关于抗生素耐药性，合并流行率最高的是环丙沙星（86.6%），其次是克林霉素（42.6%）和红霉素（34%）。甲硝唑（7.6%）、万古霉素（6.6%）和氯霉素（6%）的合并流行率最低。
发现对艰难梭菌感染（CDI）治疗常用药物的耐药性较低。由于每种抗生素都可能是CDI发生的诱发因素，从“同一个健康”的角度来看，这一发现可能警示在从农场到餐桌的链条（包括农业、畜牧业和食品工业）中抗生素的滥用，以及在医学上的不当使用。
