Department of Geriatric Medicine, National Center for Geriatrics and Gerontology, 7-430, Morioka-cho, Obu, Aichi, 474-8511, Japan.
Department of Community Healthcare and Geriatrics, Graduate School of Medicine, Nagoya University, 65 Tsurumai-cho, Showa-ku, Nagoya, Aichi, 466-8550, Japan.
Eur Geriatr Med. 2024 Aug;15(4):1119-1127. doi: 10.1007/s41999-024-00956-5. Epub 2024 Mar 5.
This study aimed to investigate how intrinsic capacity (IC) deficit is associated with oral functional decline.
This cross-sectional study enrolled older adults at a research hospital frailty clinic between July 2021 and May 2023. IC evaluation included the locomotion, cognition, vitality, psychology, and sensory domains. Criteria for deficits were established within each domain, and the number of IC deficit domains was calculated for each patient. Oral function assessment included oral hygiene, oral dryness, occlusal force, tongue-lip motor function, tongue pressure, masticatory function, and swallowing function. Patients who met three or more criteria were classified into the oral hypofunction (OHF) group. Univariate and multivariate logistic regression analyses were performed to investigate the relationship between IC deficit and OHF.
Of 222 included patients (mean age 78.3 ± 6.3 years; 39.6% men), 105 (47.3%) met the criteria for OHF. This OHF group showed a significantly higher prevalence of locomotion, cognition, psychology, and sensory domain deficits than the normal oral function group. Multivariate analysis adjusted for age and sex revealed a significant association between IC deficits and OHF (odds ratio [OR], 1.33; 95% confidence interval [CI] 1.04-1.70). A significant association was also observed between the locomotion domain and OHF (OR, 2.06; 95% CI 1.13-3.76).
This study highlights the potential relationship between the number of IC domain deficits and oral functional decline, with the most significant domain being locomotion. Furthermore, it suggests a possible link between sensory and oral function.
本研究旨在探讨内在能力（IC）缺陷与口腔功能下降的关系。
本横断面研究于 2021 年 7 月至 2023 年 5 月在一家研究医院的虚弱诊所招募了老年人。IC 评估包括运动、认知、活力、心理和感觉等领域。每个领域都确定了缺陷标准，并为每个患者计算了 IC 缺陷领域的数量。口腔功能评估包括口腔卫生、口腔干燥、咬合力、唇舌运动功能、舌压、咀嚼功能和吞咽功能。符合三项或更多标准的患者被归类为口腔功能减退（OHF）组。进行单变量和多变量逻辑回归分析，以探讨 IC 缺陷与 OHF 的关系。
在 222 名纳入的患者中（平均年龄 78.3±6.3 岁，39.6%为男性），有 105 名（47.3%）符合 OHF 的标准。OHF 组在运动、认知、心理和感觉等领域的缺陷发生率明显高于正常口腔功能组。调整年龄和性别后进行多变量分析显示，IC 缺陷与 OHF 之间存在显著关联（比值比 [OR]，1.33；95%置信区间 [CI]，1.04-1.70）。运动领域与 OHF 之间也存在显著关联（OR，2.06；95% CI，1.13-3.76）。
本研究强调了 IC 缺陷数量与口腔功能下降之间的潜在关系，其中运动领域的影响最为显著。此外，研究还提示了感觉和口腔功能之间可能存在联系。
