• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Trimethoprim resistance plasmids of different origin encode different drug-resistant dihydrofolate reductases.

作者信息

Tennhammar-Ekman B, Sköld O

出版信息

Plasmid. 1979 Jul;2(3):334-46. doi: 10.1016/0147-619x(79)90017-9.

DOI:10.1016/0147-619x(79)90017-9
PMID:384416
Abstract
摘要

相似文献

1
Trimethoprim resistance plasmids of different origin encode different drug-resistant dihydrofolate reductases.不同来源的甲氧苄啶耐药质粒编码不同的耐药二氢叶酸还原酶。
Plasmid. 1979 Jul;2(3):334-46. doi: 10.1016/0147-619x(79)90017-9.
2
Two distinct types of trimethoprim-resistant dihydrofolate reductase specified by R-plasmids of different compatibility groups.由不同相容性群的R质粒所确定的两种不同类型的耐甲氧苄啶二氢叶酸还原酶。
J Biol Chem. 1977 Apr 10;252(7):2319-23.
3
Cloning of dihydrofolate reductase gene of Escherichia coli K12.大肠杆菌K12二氢叶酸还原酶基因的克隆
J Biochem. 1982 Apr;91(4):1205-12. doi: 10.1093/oxfordjournals.jbchem.a133804.
4
Construction of plasmid vectors for cloning of promoters using the dihydrofolate reductase gene of Escherichia coli K-12.
J Biochem. 1983 Mar;93(3):927-30. doi: 10.1093/jb/93.3.927.
5
R-factor mediated dihydrofolate reductases which confer trimethoprim resistance.
J Gen Microbiol. 1978 Aug;107(2):263-71. doi: 10.1099/00221287-107-2-263.
6
Protein expression in Escherichia coli minicells containing recombinant plasmids specifying trimethoprim-resistant dihydrofolate reductases.在含有指定抗甲氧苄啶二氢叶酸还原酶的重组质粒的大肠杆菌微小细胞中的蛋白质表达。
J Bacteriol. 1980 Feb;141(2):779-85. doi: 10.1128/jb.141.2.779-785.1980.
7
Classification of trimethoprim-resistant dihydrofolate reductases mediated by R-plasmids using isoelectric focussing.使用等电聚焦法对由R质粒介导的耐甲氧苄啶二氢叶酸还原酶进行分类。
Eur J Biochem. 1982 Jul;125(3):617-22. doi: 10.1111/j.1432-1033.1982.tb06727.x.
8
[Comparative topography of the catalytic sites of chromosomal dihydrofolate reductases and that of the enzyme encoded in R 67 plasmid from E. coli].[染色体二氢叶酸还原酶催化位点与大肠杆菌R 67质粒编码酶催化位点的比较拓扑学]
C R Acad Sci III. 1988;306(13):385-90.
9
Nucleotide sequence of dihydrofolate reductase genes from trimethoprim-resistant mutants of Escherichia coli. Evidence that dihydrofolate reductase interacts with another essential gene product.来自大肠杆菌甲氧苄啶抗性突变体的二氢叶酸还原酶基因的核苷酸序列。二氢叶酸还原酶与另一种必需基因产物相互作用的证据。
Mol Gen Genet. 1982;187(1):72-8. doi: 10.1007/BF00384386.
10
Regulatory changes in the formation of chromosomal dihydrofolate reductase causing resistance to trimethoprim.导致对甲氧苄啶耐药的染色体二氢叶酸还原酶形成过程中的调控变化。
J Bacteriol. 1984 Jul;159(1):184-90. doi: 10.1128/jb.159.1.184-190.1984.

引用本文的文献

1
Mutations in the dihydrofolate reductase gene of trimethoprim-resistant isolates of Streptococcus pneumoniae.耐甲氧苄啶肺炎链球菌分离株二氢叶酸还原酶基因的突变
Antimicrob Agents Chemother. 1997 Nov;41(11):2406-13. doi: 10.1128/AAC.41.11.2406.
2
Characterization of transposon Tn5086, carrying the site-specifically inserted gene dhfrVII mediating trimethoprim resistance.携带位点特异性插入基因dhfrVII介导甲氧苄啶抗性的转座子Tn5086的特性分析。
J Bacteriol. 1993 Mar;175(6):1796-805. doi: 10.1128/jb.175.6.1796-1805.1993.
3
Characterization of different plasmid-borne dihydropteroate synthases mediating bacterial resistance to sulfonamides.
介导细菌对磺胺类药物耐药性的不同质粒携带二氢蝶酸合酶的特性分析。
J Bacteriol. 1980 Apr;142(1):1-7. doi: 10.1128/jb.142.1.1-7.1980.
4
Protein expression in Escherichia coli minicells containing recombinant plasmids specifying trimethoprim-resistant dihydrofolate reductases.在含有指定抗甲氧苄啶二氢叶酸还原酶的重组质粒的大肠杆菌微小细胞中的蛋白质表达。
J Bacteriol. 1980 Feb;141(2):779-85. doi: 10.1128/jb.141.2.779-785.1980.
5
Co-trimoxazole (trimethoprim-sulfamethoxazole): an updated review of its antibacterial activity and clinical efficacy.复方新诺明（甲氧苄啶-磺胺甲恶唑）：抗菌活性及临床疗效的最新综述
Drugs. 1982 Dec;24(6):459-518. doi: 10.2165/00003495-198224060-00002.
6
Plasmid-determined resistance to antimicrobial drugs and toxic metal ions in bacteria.质粒介导的细菌对抗菌药物和有毒金属离子的耐药性
Microbiol Rev. 1983 Sep;47(3):361-409. doi: 10.1128/mr.47.3.361-409.1983.
7
Regulatory changes in the formation of chromosomal dihydrofolate reductase causing resistance to trimethoprim.导致对甲氧苄啶耐药的染色体二氢叶酸还原酶形成过程中的调控变化。
J Bacteriol. 1984 Jul;159(1):184-90. doi: 10.1128/jb.159.1.184-190.1984.
8
Heteroduplex analysis of P-plasmid evolution: the role of insertion and deletion of transposable elements.P 质粒进化的异源双链分析：转座元件插入和缺失的作用。
Mol Gen Genet. 1983;189(3):390-9. doi: 10.1007/BF00325900.
9
Development of plasmid-mediated resistance in Vibrio cholerae during treatment with trimethoprim-sulfamethoxazole.在使用甲氧苄啶-磺胺甲恶唑治疗期间霍乱弧菌中质粒介导耐药性的发展。
Antimicrob Agents Chemother. 1985 Feb;27(2):280-1. doi: 10.1128/AAC.27.2.280.
10
Purification and characterization of dihydrofolate reductase from Mycobacterium phlei.草分枝杆菌二氢叶酸还原酶的纯化及特性研究
Biochem J. 1986 Apr 1;235(1):301-3. doi: 10.1042/bj2350301.