Acevedo Daniel, Garcia Jose R, Grewal Rajvarun S, Vankara Ashish, Murdock Christopher J, Hardigan Patrick C, Aiyer Amiethab A
Nova Southeastern University Dr. Kiran C. Patel College of Allopathic Medicine, 3200 S University Drive, Davie, FL, 33328, USA.
The Johns Hopkins University School of Medicine, Department of Orthopaedic Surgery, 4940 Eastern Avenue, Baltimore, MD, 21224, USA.
J Orthop. 2024 Feb 22;52:112-118. doi: 10.1016/j.jor.2024.02.034. eCollection 2024 Jun.
This systematic review and meta-analysis investigated the treatment for Achilles tendon rupture (ATR) associated with the lowest risk of rerupture in older patients.
Five databases were searched through September 2022 for studies published in the past 10 years analyzing operative and nonoperative ATR treatment. Studies were categorized as "nonelderly" if they reported only on patients aged 18-60 years. Studies that included at least 1 patient older than age 70 were categorized as "elderly inclusive." Of 212 studies identified, 28 were eligible for inclusion. Of 2965 patients, 1165 were treated operatively: 429 (37%) from elderly-inclusive studies and 736 (63%) from nonelderly studies. Of the 1800 nonoperative patients 553 (31%) were from nonelderly studies and 1247 (69%) were from elderly-inclusive studies.
For nonoperative treatment, the rate of rerupture was higher in nonelderly studies (83/1000 cases, 95% CI = 58, 113) than in elderly-inclusive studies (38/1000 cases, 95% CI = 22, 58; <.001). For operative treatment no difference was found in the rate of rerupture between nonelderly studies (7/1000 cases, 95% CI = 0, 21) and elderly-inclusive studies (12/1000 cases, 95% CI = 0, 35; <.78). Overall, operative treatment was associated with a rerupture rate of 1.5% (95% CI: 1.0%, 2.8%) (<.001), which was lower than the 5% rate reported by other studies for nonoperative management (<.001).
Older patients may benefit more than younger patients from nonoperative treatment of ATR. More studies are needed to determine the age at which rerupture rates decrease among nonoperatively treated patients.
本系统评价和荟萃分析研究了老年患者跟腱断裂(ATR)再断裂风险最低的治疗方法。
检索了5个数据库,截至2022年9月,查找过去10年发表的分析跟腱断裂手术和非手术治疗的研究。如果研究仅报告了18至60岁患者,则分类为“非老年”研究。纳入了至少1例70岁以上患者的研究分类为“包含老年患者”研究。在检索到的212项研究中,28项符合纳入标准。在2965例患者中,1165例接受了手术治疗:429例(37%)来自包含老年患者的研究,736例(63%)来自非老年研究。在1800例非手术治疗的患者中,553例(31%)来自非老年研究,1247例(69%)来自包含老年患者的研究。
对于非手术治疗,非老年研究中的再断裂率(83/1000例,95%CI = 58, 113)高于包含老年患者的研究(38/1000例,95%CI = 22, 58;P <.001)。对于手术治疗,非老年研究(7/1000例,95%CI = 0, 21)和包含老年患者的研究(12/1000例,95%CI = 0, 35;P <.78)之间的再断裂率没有差异。总体而言,手术治疗的再断裂率为1.5%(95%CI:1.0%,2.8%)(P <.001),低于其他研究报道的非手术治疗5%的再断裂率(P <.001)。
老年患者可能比年轻患者从跟腱断裂的非手术治疗中获益更多。需要更多研究来确定非手术治疗患者再断裂率下降的年龄。
3级