Nursing Research, PICC Excellence,Inc. Griffith University, Brisbane, Queensland, Australia.
Expert Rev Med Devices. 2024 Mar;21(3):207-216. doi: 10.1080/17434440.2024.2324885. Epub 2024 Mar 6.
More than 30% of peripherally inserted central catheters (PICCs) and midline catheters experience complications. Most complications are related to thrombotic cellular adherence to catheter materials.
This manuscript outlines PICC and midline catheter complications, the need to reduce complications and how hydrogel catheters may provide a solution to address these unmet needs based on available evidence.
Patients commonly require PICC or midline catheters for treatment to establish a reliable form of intravenous access. Catheters, while reliable in most cases, are not without complications, including occlusion, thrombosis and infection, each related to cellular adherence to the catheter material. Hydrophilic catheter coatings and composites have been developed to mitigate these thrombotic complications, reduce adherence of blood and bacterial cells to catheters and provide greater patient safety with these devices. Hydrogel materials are highly biocompatible and have been effective in reducing cellular adherence and the formation of biofilms on surfaces. Smooth hydrophilic catheter surfaces are potentially more comfortable for the patient, with reduced friction during insertion and removal. A catheter constructed of hydrophilic biomaterial, a hydrogel composite material, may minimize thrombotic complications in PICC and midline catheters, improving catheter performance and outcomes for patients.
超过 30%的外周静脉置入中心导管(PICC)和中线导管会出现并发症。大多数并发症与血栓细胞对导管材料的黏附有关。
本文概述了 PICC 和中线导管的并发症，以及减少并发症的必要性，以及水凝胶导管如何基于现有证据为解决这些未满足的需求提供解决方案。
患者通常需要 PICC 或中线导管进行治疗，以建立可靠的静脉通路形式。在大多数情况下，导管是可靠的，但并非没有并发症，包括阻塞、血栓形成和感染，这些都与导管材料上的细胞黏附有关。已经开发出亲水导管涂层和复合材料来减轻这些血栓并发症，减少血液和细菌细胞对导管的黏附，并通过这些设备提高患者安全性。水凝胶材料具有高度的生物相容性，在减少表面细胞黏附和生物膜形成方面非常有效。光滑的亲水导管表面对患者来说可能更舒适，在插入和移除过程中摩擦更小。由亲水生物材料、水凝胶复合材料制成的导管，可能会最大限度地减少 PICC 和中线导管中的血栓并发症，改善导管的性能和患者的预后。
