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嗜银和亲银性中肠类癌肿瘤中的P物质和肠高血糖素样免疫反应性

Substance P and enteroglucagon-like immunoreactivity in argentaffin and argyrophil midgut carcinoid tumours.

作者信息

Wilander E, Grimelius L, Portela-Gomes G, Lundqvist G, Skoog V, Westermark P

出版信息

Scand J Gastroenterol Suppl. 1979;53:19-25.

PMID:384502
Abstract

The presence of serotonin, substance P and enteroglucagon was investigated in 8 argentaffin and argyrophil midgut carcinoid tumours. All tumours were argentaffin and displayed formalin-induced fluorescence indicating a content of serotonin. In addition, all 8 tumours showed substance P immunoreactivity and 7 of them enteroglucagon immunoreactivity. The results indicate that the midgut carcinoid tumours are as a rule multihormonal.

摘要

对8例嗜银和嗜银性中肠类癌肿瘤进行了5-羟色胺、P物质和肠高血糖素的检测。所有肿瘤均为嗜银性,并呈现甲醛诱导的荧光,表明含有5-羟色胺。此外,所有8例肿瘤均显示P物质免疫反应性,其中7例显示肠高血糖素免疫反应性。结果表明,中肠类癌肿瘤通常是多激素性的。

相似文献

1
Substance P and enteroglucagon-like immunoreactivity in argentaffin and argyrophil midgut carcinoid tumours.嗜银和亲银性中肠类癌肿瘤中的P物质和肠高血糖素样免疫反应性
Scand J Gastroenterol Suppl. 1979;53:19-25.
2
Endocrine cells of the gastrointestinal tract and their pathology.胃肠道内分泌细胞及其病理学
Pathol Annu. 1978;13 Pt 2:329-50.
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Virchows Arch B Cell Pathol. 1977 Oct 27;25(2):117-24. doi: 10.1007/BF02889426.
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Serotonin in fore-gut carcinoids. A survey of 60 cases with regard to silver stains, formalin-induced fluorescence and serotonin immunocytochemistry.前肠类癌中的5-羟色胺。关于银染、甲醛诱导荧光和5-羟色胺免疫细胞化学的60例病例调查。
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Polypeptide hormones in argentaffin and argyrophil gastroduodenal endocrine tumors.嗜银和嗜银性胃肠内分泌肿瘤中的多肽激素。
Am J Pathol. 1979 Aug;96(2):519-30.
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Small intestinal chromaffin cells and carcinoid tumours: a study with silver stains, formalin-induced fluorescence and monoclonal antibodies to serotonin.小肠嗜铬细胞与类癌肿瘤:一项关于银染色、福尔马林诱导荧光及血清素单克隆抗体的研究
Histochem J. 1984 Dec;16(12):1247-56. doi: 10.1007/BF01003723.
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Argentaffin and argyrophil reactions and serotonin content of endocrine tumours.内分泌肿瘤的嗜银和嗜银反应及5-羟色胺含量
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Substance P and 5-HT in granules isolated from an intestinal argentaffin carcinoid.从肠道嗜银类癌中分离出的颗粒中的P物质和5-羟色胺
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Carcinoid tumours of the gastrointestinal tract.胃肠道类癌肿瘤
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引用本文的文献

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A novel tachykinin NK2 receptor antagonist prevents motility-stimulating effects of neurokinin A in small intestine.一种新型速激肽NK2受体拮抗剂可预防神经激肽A对小肠的促动力作用。
Br J Pharmacol. 2001 Sep;134(1):215-23. doi: 10.1038/sj.bjp.0704217.
2
Small intestinal chromaffin cells and carcinoid tumours: a study with silver stains, formalin-induced fluorescence and monoclonal antibodies to serotonin.小肠嗜铬细胞与类癌肿瘤:一项关于银染色、福尔马林诱导荧光及血清素单克隆抗体的研究
Histochem J. 1984 Dec;16(12):1247-56. doi: 10.1007/BF01003723.
3
The effect of carcinoid levels of serotonin and substance P on hemodynamics.
类癌水平的血清素和P物质对血流动力学的影响。
Ann Surg. 1984 Feb;199(2):197-204. doi: 10.1097/00000658-198402000-00012.
4
Substance P in the argentaffin carcinoid of the caecum: biochemical and biological characterization.盲肠嗜银性类癌中的P物质:生化及生物学特性
Virchows Arch A Pathol Anat Histol. 1981;392(1):21-31. doi: 10.1007/BF00430545.
5
Human pancreatic polypeptide (HPP) immunoreactivity in an infiltrating endocrine tumour of the papilla of Vater with unusual morphology.
Virchows Arch A Pathol Anat Histol. 1981;392(1):119-26. doi: 10.1007/BF00430555.
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Use of somatostatin analog in management of carcinoid syndrome.生长抑素类似物在类癌综合征管理中的应用。
Dig Dis Sci. 1989 Mar;34(3 Suppl):14S-27S. doi: 10.1007/BF01536042.
7
Substance P-induced intestinal secretion of water and electrolytes.P物质诱导的肠道水和电解质分泌。
Gut. 1986 Mar;27(3):267-72. doi: 10.1136/gut.27.3.267.