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嗜银和亲银性中肠类癌肿瘤中的P物质和肠高血糖素样免疫反应性

Substance P and enteroglucagon-like immunoreactivity in argentaffin and argyrophil midgut carcinoid tumours.

作者信息

Wilander E, Grimelius L, Portela-Gomes G, Lundqvist G, Skoog V, Westermark P

出版信息

Scand J Gastroenterol Suppl. 1979;53:19-25.

PMID:384502
Abstract

The presence of serotonin, substance P and enteroglucagon was investigated in 8 argentaffin and argyrophil midgut carcinoid tumours. All tumours were argentaffin and displayed formalin-induced fluorescence indicating a content of serotonin. In addition, all 8 tumours showed substance P immunoreactivity and 7 of them enteroglucagon immunoreactivity. The results indicate that the midgut carcinoid tumours are as a rule multihormonal.

摘要

对8例嗜银和嗜银性中肠类癌肿瘤进行了5-羟色胺、P物质和肠高血糖素的检测。所有肿瘤均为嗜银性,并呈现甲醛诱导的荧光,表明含有5-羟色胺。此外,所有8例肿瘤均显示P物质免疫反应性,其中7例显示肠高血糖素免疫反应性。结果表明,中肠类癌肿瘤通常是多激素性的。

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