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越南 1990 年至 2019 年抑郁障碍负担:2019 年全球疾病负担研究的二次分析。

Burden of depressive disorders in Vietnam from 1990 to 2019: A secondary analysis of the Global Burden of Disease Study 2019.

机构信息

Department of Health Data Science, Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, Okayama University, Okayama, Japan; Faculty of Pharmacy, Haiphong University of Medicine and Pharmacy, Haiphong, Viet Nam.

Department of Medicine, Icahn School of Medicine at Mount Sinai, Mount Sinai Beth Israel, New York, New York, USA.

出版信息

J Psychiatr Res. 2024 Apr;172:420-426. doi: 10.1016/j.jpsychires.2024.02.041. Epub 2024 Feb 22.

Abstract

Depressive disorders are among the leading causes of disability globally. However, information on the burden of depressive disorders in Vietnam is limited. We aimed to analyse the burden of depressive disorders in Vietnam from 1990 to 2019. Using data from the Global Burden of Disease Study 2019, prevalence and disability-adjusted life-years (DALYs) were used as indicators to analyse the burden of depressive disorders by age and sex. In 2019 in Vietnam, depressive disorders comprised 2629.1 thousand (95% uncertainty interval (UI): 2233.3-3155.9) estimated cases and 380.6 thousand (95% UI: 258.9-533.8) estimated DALYs. The crude prevalence rate of depressive disorders was higher among females than among males. The DALYs of depressive disorder accounted for a higher percentage of the total all-cause DALYs in the 10-64-year age group than in other age groups. Major depressive disorder was the largest contributor to the burden of depressive disorders. From 1990 to 2019, the crude prevalence and DALY rates per 100 000 population due to depressive disorders increased significantly, whereas age-standardised rates of prevalence and DALYs decreased significantly; the respective average annual percent changes were 0.88% (95% confidence interval: 0.87 to 0.89), 0.68% (0.66 to 0.70), -0.20% (-0.21 to -0.19), and -0.27% (-0.28 to -0.25). Although the age-standardised prevalence rate was lower than that seen globally, depressive disorders were considerable mental health issues in Vietnam. This study will help governments and policymakers to establish appropriate strategies to reduce the burden of these disorders by identifying the priority areas and individuals.

摘要

抑郁障碍是全球导致残疾的主要原因之一。然而,越南抑郁障碍负担的相关信息有限。本研究旨在分析 1990 年至 2019 年越南抑郁障碍的负担。我们使用 2019 年全球疾病负担研究的数据,使用患病率和伤残调整生命年(DALY)作为指标,按年龄和性别分析抑郁障碍的负担。2019 年,越南抑郁障碍的估计病例数为 2629.1 万(95%不确定区间(UI):2233.3-3155.9),估计 DALY 数为 380.6 万(95% UI:258.9-533.8)。女性的抑郁障碍粗患病率高于男性。10-64 岁年龄组的抑郁障碍 DALY 占总全因 DALY 的比例高于其他年龄组。重度抑郁障碍是抑郁障碍负担的最大贡献者。1990 年至 2019 年,每 10 万人因抑郁障碍导致的粗患病率和 DALY 率均显著增加,而年龄标准化患病率和 DALY 率则显著下降;相应的年均变化百分比分别为 0.88%(95%置信区间:0.87-0.89)、0.68%(0.66-0.70)、-0.20%(-0.21-0.19)和-0.27%(-0.28-0.25)。尽管年龄标准化患病率低于全球水平,但抑郁障碍仍是越南严重的精神卫生问题。本研究将有助于各国政府和决策者通过确定优先领域和人群,制定适当的策略来减轻这些疾病的负担。

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