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基于多功能 MXene 的软组织和骨组织再生与工程平台

Multifunctional MXene-Based Platforms for Soft and Bone Tissue Regeneration and Engineering.

机构信息

Independent Researcher, W Nazar ST, Boostan Avenue, Isfahan 81756-33551, Iran.

School of Chemistry, Damghan University, Damghan 36716-45667, Iran.

出版信息

ACS Biomater Sci Eng. 2024 Apr 8;10(4):1892-1909. doi: 10.1021/acsbiomaterials.3c01770. Epub 2024 Mar 11.

Abstract

MXenes and their composites hold great promise in the field of soft and bone tissue regeneration and engineering (TRE). However, there are challenges that need to be overcome, such as ensuring biocompatibility and controlling the morphologies of MXene-based scaffolds. The future prospects of MXenes in TRE include enhancing biocompatibility through surface modifications, developing multifunctional constructs, and conducting studies for clinical translation. The purpose of this perspective about MXenes and their composites in soft and bone TRE is to critically evaluate their potential applications and contributions in this field. This perspective aims to provide a comprehensive analysis of the challenges, advantages, limitations, and future prospects associated with the use of MXenes and their composites for soft and bone TRE. By examining the existing literature and research, the review seeks to consolidate the current knowledge and highlight the key findings and advancements in MXene-based TRE. It aims to contribute to the understanding of MXenes' role in promoting soft and bone TRE, addressing the challenges faced in terms of biocompatibility, morphology control, and tissue interactions.

摘要

MXenes 及其复合材料在软组织和骨组织再生与工程(TRE)领域具有广阔的应用前景。然而,仍存在一些需要克服的挑战,如确保生物相容性和控制 MXene 基支架的形态。MXenes 在 TRE 中的未来前景包括通过表面改性提高生物相容性、开发多功能构建体以及进行临床转化研究。本文旨在对 MXenes 及其复合材料在软组织和骨 TRE 中的潜在应用和贡献进行批判性评估。本综述旨在提供对使用 MXenes 和其复合材料进行软组织和骨 TRE 的相关挑战、优势、局限性和未来前景的全面分析。通过研究现有文献和研究,综述旨在整合当前的知识,并突出基于 MXene 的 TRE 的关键发现和进展。本文旨在为理解 MXenes 在促进软组织和骨 TRE 中的作用、解决生物相容性、形态控制和组织相互作用方面面临的挑战做出贡献。

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