Furihata Ryuji, Shimamoto Tomonari, Makino Yuto, Kimata Shunsuke, Tateyama Yukiko, Okabayashi Satoe, Kiyohara Kosuke, Iwami Taku
Agency for Student Support and Disability Resources, Kyoto University, Yoshida-Honmachi, Sakyo-Ku, Kyoto, 606-8501 Japan.
Department of Preventive Services, Kyoto University School of Public Health, Graduate School of Medicine, Kyoto, Japan.
Sleep Biol Rhythms. 2023 Feb 21;21(3):359-368. doi: 10.1007/s41105-023-00453-5. eCollection 2023 Jul.
The efficacy of sleep extension therapy using a remote support system (SET-R) was investigated in university students with increased social jetlag (SJL).
For this two-arm parallel randomized controlled trial, we recruited Japanese university students with SJL ≥ 60 min. The SET-R provided an individualized sleep schedule for gradual sleep extension using email and sleep hygiene education, stimulus control therapy, and progressive muscle relaxation as web content. The control group was sent an email that encouraged them to record their sleep. The duration of the intervention program was two weeks. The primary outcome was the mean change in SJL two weeks later, assessed using the Munich ChronoType Questionnaire (MCTQ). The other outcomes included Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale (ESS), Insomnia Severity Index, Patient Health Questionnaire-9 (PHQ-9), and sleep quiz. A follow-up survey was conducted 6 months after the intervention.
Of 54 students, 26 were assigned to an intervention group and 28 to a control group. The difference in the mean change in SJL between the two groups ( = 26, = 27) at two weeks was statistically significant (27.7 min, = 0.048). The scores for the ESS, PHQ-9, and sleep quiz were improved in the intervention group relative to the control group. At the 6-month follow-up point, the difference in the mean change in SJL between the two groups ( = 22, = 27) was not statistically significant, but scores for the PHQ-9, and sleep quiz remained significant.
This study demonstrated the efficacy of the SET-R among university students with increased SJL.
The study was registered with the UMIN Clinical Trials Registry (UMIN000042634, 2021/02/01).
在社交时差增加（SJL）的大学生中研究使用远程支持系统的睡眠延长疗法（SET-R）的疗效。
在这项双臂平行随机对照试验中，我们招募了SJL≥60分钟的日本大学生。SET-R通过电子邮件提供个性化的睡眠时间表，用于逐步延长睡眠时间，并提供睡眠卫生教育、刺激控制疗法和渐进性肌肉松弛等网络内容。对照组收到一封鼓励他们记录睡眠的电子邮件。干预计划为期两周。主要结局是两周后使用慕尼黑时间类型问卷（MCTQ）评估的SJL平均变化。其他结局包括匹兹堡睡眠质量指数、爱泼华嗜睡量表（ESS）、失眠严重程度指数、患者健康问卷-9（PHQ-9）和睡眠测验。干预后6个月进行随访调查。
54名学生中，26名被分配到干预组，28名被分配到对照组。两组在两周时SJL平均变化的差异（干预组n = 26，对照组n = 27）具有统计学意义（27.7分钟，P = 0.048）。干预组的ESS、PHQ-9和睡眠测验得分相对于对照组有所改善。在6个月的随访点，两组之间SJL平均变化的差异（干预组n = 22，对照组n = 27）无统计学意义，但PHQ-9和睡眠测验得分仍有显著差异。
本研究证明了SET-R在SJL增加的大学生中的疗效。
该研究已在UMIN临床试验注册中心注册（UMIN000042634，2021/02/01）。
