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基于便携式空调的生物防护设备,用于预防急性和长期医疗机构、公共集会场所、公共交通及类似场所中的空气传播感染。

Portable and Air Conditioner-Based Bio-Protection Devices to Prevent Airborne Infections in Acute and Long-Term Healthcare Facilities, Public Gathering Places, Public Transportation, and Similar Entities.

作者信息

Pisharodi Madhavan

机构信息

Neurosurgery, South Texas Neurosurgery Associates, Brownsville, USA.

出版信息

Cureus. 2024 Mar 11;16(3):e55950. doi: 10.7759/cureus.55950. eCollection 2024 Mar.

Abstract

The nature in which the coronavirus disease 2019 (COVID-19) pandemic started and spread all over the world has surprised and shocked experts and the general population alike. This has brought out a worldwide desire and serious efforts to prevent, or at least reduce, the severity of another airborne viral infection and protect individuals gathering for various reasons. Toward this main purpose, a novel method to disinfect the air, using graded, predictable, safe, and reliable dosage of ultraviolet C (UVC), with specially designed devices, is described here. Individuals exclusively breathing this disinfected air can prevent infection, thus destroying the airborne virus or any other pathogens outside the human body to prevent acute and chronic damage to the organs and provide a sense of security to congregate, use public transport, and be protected in acute and long-term healthcare facilities. The study involved designing and testing a unit with one UVC chamber and another unit with six UVC chambers both enclosed in UVC-opaque housings that could be used to destroy airborne pathogens. Wild-type severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was used as a representative pathogen. The virus was fed into these units and in both units, the virus was destroyed to undetectable levels. Such disinfected air can be made available for individuals to breathe at an individual and a community level. The two units that were studied were able to destroy the SARS-CoV-2 virus completely in UVC-opaque housings, making them safe for human use. By employing the air to bring the virus to the UVC, the problem of the virus getting protected behind structures was avoided. The individuals get to breathe totally disinfected air through a mask or a ventilator. To protect individuals who are unable or unwilling to use these units meant for individual use, the same principle can be expanded for use with air conditioners to provide community protection. It is envisaged that this method can prevent airborne infections from turning into pandemics and is a clear example of advocating prevention, rather than treatment. These units are expandable and the UVC dosage to the pathogen can be adjusted and predictable, thereby making it a standard technique to study the dosage needed to inactivate different pathogens.

摘要

2019冠状病毒病(COVID-19)大流行在全球范围内开始并传播的方式令专家和普通民众都感到惊讶和震惊。这引发了全球范围内的一种愿望以及为预防或至少减轻另一种空气传播病毒感染的严重程度、保护因各种原因聚集的个人而做出的认真努力。为了实现这一主要目标,本文介绍了一种使用经过分级、可预测、安全且可靠剂量的紫外线C(UVC)以及专门设计的设备对空气进行消毒的新方法。仅呼吸这种经过消毒空气的个体可以预防感染,从而在人体外消灭空气传播的病毒或任何其他病原体,以防止对器官造成急性和慢性损害,并为聚集、使用公共交通工具以及在急性和长期医疗保健设施中获得保护提供安全感。该研究涉及设计和测试一个带有一个UVC腔室的单元以及另一个带有六个UVC腔室的单元,这两个单元都封闭在不透UVC的外壳中,可用于消灭空气传播的病原体。野生型严重急性呼吸综合征冠状病毒2(SARS-CoV-2)被用作代表性病原体。将病毒输入这些单元,在两个单元中,病毒均被消灭至检测不到的水平。这样经过消毒的空气可在个人和社区层面供个体呼吸。所研究的这两个单元能够在不透UVC的外壳中完全消灭SARS-CoV-2病毒,使其对人类使用安全。通过利用空气将病毒带到UVC处,避免了病毒在结构后面得到保护的问题。个体通过口罩或呼吸机呼吸完全经过消毒的空气。为了保护那些无法或不愿意使用这些供个人使用的单元的个体,可以将相同原理扩展到与空调配合使用以提供社区保护。预计这种方法可以防止空气传播感染演变成大流行,并且是倡导预防而非治疗的一个明显例子。这些单元是可扩展的,并且对病原体的UVC剂量可以调整且可预测,从而使其成为研究灭活不同病原体所需剂量的标准技术。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/394d/10926937/986478f6e8b9/cureus-0016-00000055950-i01.jpg

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