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J Clin Gastroenterol. 2023 Aug 1;57(7):663-670. doi: 10.1097/MCG.0000000000001855.
2
Gut microbiota and its metabolites in depression: from pathogenesis to treatment.肠道微生物群及其代谢物与抑郁症:从发病机制到治疗。
EBioMedicine. 2023 Apr;90:104527. doi: 10.1016/j.ebiom.2023.104527. Epub 2023 Mar 22.
3
Probiotics as a Tool for Regulating Molecular Mechanisms in Depression: A Systematic Review and Meta-Analysis of Randomized Clinical Trials.益生菌作为调节抑郁症分子机制的工具:随机临床试验的系统评价和荟萃分析。
Int J Mol Sci. 2023 Feb 4;24(4):3081. doi: 10.3390/ijms24043081.
4
The promotion mechanism of prebiotics for probiotics: A review.益生元对益生菌的促进机制:综述
Front Nutr. 2022 Oct 5;9:1000517. doi: 10.3389/fnut.2022.1000517. eCollection 2022.
5
Characteristics of Probiotic Preparations and Their Applications.益生菌制剂的特性及其应用
Foods. 2022 Aug 16;11(16):2472. doi: 10.3390/foods11162472.
6
Microbiological Testing of Probiotic Preparations.益生菌制剂的微生物检测
Int J Environ Res Public Health. 2022 May 7;19(9):5701. doi: 10.3390/ijerph19095701.
7
The Gut Microbiome in Depression and Potential Benefit of Prebiotics, Probiotics and Synbiotics: A Systematic Review of Clinical Trials and Observational Studies.抑郁症中的肠道微生物组及益生菌、益生元和合生制剂的潜在益处:临床试验和观察性研究的系统评价。
Int J Mol Sci. 2022 Apr 19;23(9):4494. doi: 10.3390/ijms23094494.
8
Clinician guidelines for the treatment of psychiatric disorders with nutraceuticals and phytoceuticals: The World Federation of Societies of Biological Psychiatry (WFSBP) and Canadian Network for Mood and Anxiety Treatments (CANMAT) Taskforce.临床医生使用营养保健品和植物药治疗精神障碍的指南:世界生物精神病学学会联合会(WFSBP)和加拿大心境与焦虑治疗网(CANMAT)工作组。
World J Biol Psychiatry. 2022 Jul;23(6):424-455. doi: 10.1080/15622975.2021.2013041. Epub 2022 Mar 21.
9
Association Between Consumption of Fermented Food and Food-Derived Prebiotics With Cognitive Performance, Depressive, and Anxiety Symptoms in Psychiatrically Healthy Medical Students Under Psychological Stress: A Prospective Cohort Study.心理压力下精神健康的医学生食用发酵食品和食物源益生元与认知能力、抑郁及焦虑症状之间的关联:一项前瞻性队列研究
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The microbiota-gut-brain axis: pathways to better brain health. Perspectives on what we know, what we need to investigate and how to put knowledge into practice.肠道菌群-肠-脑轴:通往更好脑健康的途径。了解我们所知道的、需要研究的以及如何将知识付诸实践的视角。
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益生菌和益生元对精神与肠道健康的影响。

Probiotics and Prebiotics Affecting Mental and Gut Health.

作者信息

İnce Palamutoglu Merve, Köse Gizem, Bas Murat

机构信息

Department of Nutrition and Dietetics, Institute of Health Sciences, Acibadem Mehmet Ali Aydinlar University, Istanbul 34752, Türkiye.

Department of Nutrition and Dietetics, Faculty of Health Sciences, Afyonkarahisar Health Sciences University, Afyonkarahisar 03030, Türkiye.

出版信息

Healthcare (Basel). 2024 Feb 21;12(5):510. doi: 10.3390/healthcare12050510.

DOI:10.3390/healthcare12050510
PMID:38470623
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10931157/
Abstract

The effects of the gut microbiota on mental and intestinal health are an area of great interest. This study aimed to reveal the relationship between the intake of probiotic and prebiotic foods and mental and gut health. Data were obtained using an online survey from young adults (n = 538) enrolled at Afyonkarahisar Health Sciences University who agreed to participate in this study in the 2022-2023 academic year. This study included 538 participants, mostly (85.5%) females. Participants who never consumed yogurt had 7.614 times higher Gastrointestinal Symptom Rating Scale scores than those who consumed yogurt daily ( < 0.01). Similarly, the frequency of ayran consumption had a statistically significant effect on Bristol Stool Scale scores ( < 0.05). The ratio of normal defecation to constipation was 68.7% lower in participants who consumed ayran daily, whereas the ratio of diarrhea to constipation was 76.4% lower in participants who never consumed ayran. However, the frequency of prebiotic consumption did not have a significant effect on Bristol Stool Scale scores ( > 0.05). The consumption of probiotic and prebiotic foods exerted a significant effect on GSRS total scores and subfactors of the Depression Anxiety Stress Scale-42, namely depression, anxiety, and stress.

摘要

肠道微生物群对精神和肠道健康的影响是一个备受关注的领域。本研究旨在揭示益生菌和益生元食物的摄入量与精神和肠道健康之间的关系。数据通过在线调查获得,调查对象为阿菲永卡拉希萨尔健康科学大学在2022 - 2023学年同意参与本研究的年轻人(n = 538)。本研究包括538名参与者,其中大多数(85.5%)为女性。从未食用过酸奶的参与者的胃肠道症状评分量表得分比每天食用酸奶的参与者高7.614倍(< 0.01)。同样, ayran(一种土耳其传统发酵乳饮料)的食用频率对布里斯托大便分类法评分有统计学上的显著影响(< 0.05)。每天食用ayran的参与者正常排便与便秘的比例比从未食用ayran的参与者低68.7%,而腹泻与便秘的比例比从未食用ayran的参与者低76.4%。然而,益生元的食用频率对布里斯托大便分类法评分没有显著影响(> 0.05)。益生菌和益生元食物的食用对抑郁焦虑压力量表 - 42(DASS - 42)的总分和子因素,即抑郁、焦虑和压力,有显著影响。