• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Lactylation regulated DNA damage repair and cancer cell chemosensitivity.

作者信息

Liu Zichao, Huang Yile, Liu Xingguo

机构信息

CAS Key Laboratory of Regenerative Biology, Joint School of Life Sciences, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou Medical University, Guangzhou 510530, China; Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences, Hong Kong 999077, China; Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangdong-Hong Kong Joint Laboratory for Stem Cell and Regenerative Medicine, China-New Zealand Joint Laboratory on Biomedicine and Health, CUHK-GIBH Joint Research Laboratory on Stem Cells and Regenerative Medicine, GIBH-HKU Guangdong-Hong Kong Stem Cell and Regenerative Medicine Research Centre, Institute for Stem Cell and Regeneration, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China; University of Chinese Academy of Sciences, Beijing 100049, China.

Centre for Regenerative Medicine and Health, Hong Kong Institute of Science & Innovation, Chinese Academy of Sciences, Hong Kong 999077, China.

出版信息

Sci Bull (Beijing). 2024 May 15;69(9):1185-1187. doi: 10.1016/j.scib.2024.02.037. Epub 2024 Feb 29.

DOI:10.1016/j.scib.2024.02.037
PMID:38472020
Abstract
摘要

相似文献

1
Lactylation regulated DNA damage repair and cancer cell chemosensitivity.乳酰化作用调节DNA损伤修复及癌细胞的化学敏感性。
Sci Bull (Beijing). 2024 May 15;69(9):1185-1187. doi: 10.1016/j.scib.2024.02.037. Epub 2024 Feb 29.
2
Cancer, DNA repair mechanisms, and resistance to chemotherapy.癌症、DNA修复机制与化疗耐药性
J Natl Cancer Inst. 2001 Oct 3;93(19):1434-6. doi: 10.1093/jnci/93.19.1434.
3
Connecting dots between nucleotide biosynthesis and DNA lesion repair/bypass in cancer.在癌症中连接核苷酸生物合成与 DNA 损伤修复/绕过之间的联系。
Biosci Rep. 2024 Sep 25;44(9). doi: 10.1042/BSR20231382.
4
Strategies for targeting the DNA damage response for cancer therapeutics.针对癌症治疗的DNA损伤反应的靶向策略。
Chin J Cancer. 2012 Aug;31(8):359-63. doi: 10.5732/cjc.012.10087. Epub 2012 Jun 14.
5
As easy as ABC: scientists fish out another drug resistance gene.易如反掌：科学家又找出一个耐药基因。
J Natl Cancer Inst. 1999 Mar 3;91(5):402-4. doi: 10.1093/jnci/91.5.402.
6
Mismatch repair and response to DNA-damaging antitumour therapies.错配修复与对DNA损伤性抗肿瘤疗法的反应
Eur J Cancer. 2003 Oct;39(15):2142-9. doi: 10.1016/s0959-8049(03)00569-0.
7
MMSET/WHSC1 enhances DNA damage repair leading to an increase in resistance to chemotherapeutic agents.MMSET/WHSC1增强DNA损伤修复，导致对化疗药物的抗性增加。
Oncogene. 2016 Nov 10;35(45):5905-5915. doi: 10.1038/onc.2016.116. Epub 2016 Apr 25.
8
Resistance mechanisms to cancer chemotherapy.癌症化疗的耐药机制
Front Biosci. 2008 May 1;13:5138-54. doi: 10.2741/3070.
9
Targeting DNA Damage Response and Repair to Enhance Therapeutic Index in Cisplatin-Based Cancer Treatment.针对 DNA 损伤反应和修复以提高顺铂类癌症治疗的治疗指数。
Int J Mol Sci. 2021 Jul 30;22(15):8199. doi: 10.3390/ijms22158199.
10
The effects of deregulated DNA damage signalling on cancer chemotherapy response and resistance.DNA 损伤信号失调对癌症化疗反应和耐药性的影响。
Nat Rev Cancer. 2012 Sep;12(9):587-98. doi: 10.1038/nrc3342.

引用本文的文献

1
Lactylation in Glioblastoma: A Novel Epigenetic Modifier Bridging Epigenetic Plasticity and Metabolic Reprogramming.胶质母细胞瘤中的乳酸化：一种连接表观遗传可塑性和代谢重编程的新型表观遗传修饰因子
Int J Mol Sci. 2025 Apr 4;26(7):3368. doi: 10.3390/ijms26073368.
2
Integration of scRNA-seq and bulk RNA-seq to reveal the association and potential molecular mechanisms of metabolic reprogramming regulated by lactylation and chemotherapy resistance in ovarian cancer.整合单细胞RNA测序和批量RNA测序以揭示乳酸化调控的代谢重编程与卵巢癌化疗耐药之间的关联及潜在分子机制。
Front Immunol. 2025 Feb 28;16:1513806. doi: 10.3389/fimmu.2025.1513806. eCollection 2025.
3
Identification of a novel lactylation-related gene signature predicts the prognosis of multiple myeloma and experiment verification.
鉴定新型乳糖化相关基因特征可预测多发性骨髓瘤的预后并经实验验证。
Sci Rep. 2024 Jul 2;14(1):15142. doi: 10.1038/s41598-024-65937-x.