Carrillo-Martinez Eber Josue, Flores-Hernández Flor Yohana, Salazar-Montes Adriana María, Nario-Chaidez Hector Fabián, Hernández-Ortega Luis Daniel
Unidad de Biotecnología Médica y Farmacéutica, Centro de Investigación y Asistencia en Tecnología y Diseño del Estado de Jalisco, Guadalajara 44270, Mexico.
Instituto de Investigación en Enfermedades Crónico-Degenerativas, Centro de Universitario de Ciencias de la Salud, Universidad de Guadalajara, Sierra Mojada 950, Guadalajara 44340, Mexico.
Molecules. 2024 Feb 25;29(5):1000. doi: 10.3390/molecules29051000.
Quercetin is a flavonoid with a low molecular weight that belongs to the human diet's phenolic phytochemicals and nonenergy constituents. Quercetin has a potent antioxidant capacity, being able to capture reactive oxygen species (ROS), reactive nitrogen species (RNS), and reactive chlorine species (ROC), which act as reducing agents by chelating transition-metal ions. Its structure has five functional hydroxyl groups, which work as electron donors and are responsible for capturing free radicals. In addition to its antioxidant capacity, different pharmacological properties of quercetin have been described, such as carcinostatic properties; antiviral, antihypertensive, and anti-inflammatory properties; the ability to protect low-density lipoprotein (LDL) oxidation, and the ability to inhibit angiogenesis; these are developed in this review.
槲皮素是一种低分子量黄酮类化合物，属于人类饮食中的酚类植物化学物质和非能量成分。槲皮素具有强大的抗氧化能力，能够捕获活性氧（ROS）、活性氮（RNS）和活性氯（ROC），它通过螯合过渡金属离子作为还原剂。其结构有五个功能性羟基，这些羟基作为电子供体，负责捕获自由基。除了抗氧化能力外，槲皮素还具有不同的药理特性，如抗癌特性；抗病毒、抗高血压和抗炎特性；保护低密度脂蛋白（LDL）氧化的能力以及抑制血管生成的能力；本综述将对这些特性进行阐述。
