College of Food Science and Nutritional Engineering, China Agricultural University, Beijing 100083, China.
Sanya Institute of China Agricultural University, Sanya 572025, China.
Nutrients. 2024 Feb 29;16(5):695. doi: 10.3390/nu16050695.
L. is a widely cultivated tropical crop in Southeast Asia, and its fruit, areca nut, has been consumed as a traditional Chinese medicinal material for more than 10,000 years, although it has recently attracted widespread attention due to potential hazards. Areca nut holds a significant position in traditional medicine in many areas and ranks first among the four southern medicines in China. Numerous bioactive compounds have been identified in areca nuts, including alkaloids, polyphenols, polysaccharides, and fatty acids, which exhibit diverse bioactive functions, such as anti-bacterial, deworming, anti-viral, anti-oxidant, anti-inflammatory, and anti-tumor effects. Furthermore, they also display beneficial impacts targeting the nervous, digestive, and endocrine systems. This review summarizes the pharmacological functions and underlying mechanisms of the bioactive ingredients in areca nut. This helps to ascertain the beneficial components of areca nut, discover its medicinal potential, and guide the utilization of the areca nut.
L. 是东南亚广泛种植的热带作物,其果实槟榔作为中药材在中国已经使用了一万多年,尽管最近由于潜在的危害而引起了广泛关注。槟榔在许多地区的传统医学中占有重要地位,在中国四大南药中排名第一。槟榔中已经鉴定出许多生物活性化合物,包括生物碱、多酚、多糖和脂肪酸,它们具有多种生物活性功能,如抗菌、驱虫、抗病毒、抗氧化、抗炎和抗肿瘤作用。此外,它们还对神经系统、消化系统和内分泌系统产生有益影响。本综述总结了槟榔中生物活性成分的药理作用及其作用机制。这有助于确定槟榔的有益成分,发现其药用潜力,并指导槟榔的利用。