用于抗菌应用的含银纳米颗粒的静电纺丝丝素蛋白基纤维膜
Electrospinning Silk-Fibroin-Based Fibrous Membranes with AgNPs for Antimicrobial Application.
作者信息
Li Qing, Gong Hongyu, Jia Xiang, Wang Ran, Liu Zhiwei, Zhang Lexin, Li Jisheng, Jiao Tifeng
机构信息
Hebei Key Laboratory of Safety Monitoring of Mining Equipment, School of Emergency Equipment, North China Institute of Science and Technology, Langfang 065201, China.
State Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao 066004, China.
出版信息
Polymers (Basel). 2024 Feb 28;16(5):648. doi: 10.3390/polym16050648.
Silk fibroin (SF) has excellent biocompatibility and is one of the most commonly used polymer materials. However, SF fibers have serious drawbacks as antibacterial materials due to their lack of stability and bacterial resistance. Therefore, it is of paramount significance to enhance the stability and bolster the bacterial resistance of SF fibers. In this study, SF fibers were fabricated and loaded with Ag nanoparticles (AgNPs) to improve the antimicrobial properties of the fibers. The impact of reduction conditions on the size of AgNPs was also investigated. In an antibacterial test, the fibers that were prepared exhibited over 98% bacterial resistance against () and (). Therefore, as an efficient antibacterial material, these fibers are expected to become a candidate material in medical and textile fields. This study offers a novel approach for the utilization of SF fibers in the realm of antibacterial applications.
丝素蛋白（SF）具有优异的生物相容性，是最常用的聚合物材料之一。然而，SF纤维作为抗菌材料存在严重缺陷，因为它们缺乏稳定性和抗菌性。因此，提高SF纤维的稳定性并增强其抗菌性具有至关重要的意义。在本研究中，制备了SF纤维并负载银纳米颗粒（AgNPs）以改善纤维的抗菌性能。还研究了还原条件对AgNPs尺寸的影响。在抗菌测试中，所制备的纤维对（）和（）表现出超过98%的抗菌性。因此，作为一种高效的抗菌材料，这些纤维有望成为医学和纺织领域的候选材料。本研究为SF纤维在抗菌应用领域的利用提供了一种新方法。
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