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社区居住的独立老年人的嗅觉和味觉功能与记忆能力的相关性研究。

Association of Olfactory and Gustatory Function with Memory among Community-Dwelling Independent Older Adults.

机构信息

Department of Physical Therapy, School of Health Sciences, Kagoshima University, Kagoshima, Japan.

Department of Mechanical Systems Engineering, Faculty of Engineering, Daiichi Institute of Technology, Kagoshima, Japan.

出版信息

Ann Geriatr Med Res. 2024 Jun;28(2):178-183. doi: 10.4235/agmr.23.0217. Epub 2024 Mar 13.

Abstract

BACKGROUND

This study examined the association between memory function and reduced olfactory and gustatory function among independent community-dwelling older adults.

METHODS

This cross-sectional study included 127 older adults (65.4% women). We assessed their memory, odor, and taste identification skills. Open essence (OE) test and taste strips (TS) were used to identify hyposmia (OE test ≤6) and hypogeusia (TS test ≤8), respectively.

RESULTS

Participants with severe hyposmia had significantly poorer memory functions compared to participants without severe hyposmia. After adjusting for covariates, multivariate logistic regression models revealed a significant association between immediate recognition performance and a decreased likelihood of severe hyposmia (odds ratio=0.65; 95% confidence interval 0.47-0.90). We observed no significant association between taste function and memory.

CONCLUSION

Memory function may be associated with olfactory impairment in older adults.

摘要

背景

本研究旨在探讨独立居住的老年人群中记忆功能与嗅觉和味觉功能减退之间的关系。

方法

本横断面研究纳入了 127 名老年人(65.4%为女性)。我们评估了他们的记忆、嗅觉和味觉识别能力。使用开放式嗅觉测试(OE 测试)和味觉条(TS 测试)分别评估嗅觉减退(OE 测试≤6)和味觉减退(TS 测试≤8)。

结果

与无严重嗅觉减退的参与者相比,严重嗅觉减退的参与者记忆功能明显更差。调整混杂因素后,多元逻辑回归模型显示,即时识别表现与严重嗅觉减退的可能性降低之间存在显著关联(比值比=0.65;95%置信区间 0.47-0.90)。我们未观察到味觉功能与记忆之间存在显著关联。

结论

在老年人中,记忆功能可能与嗅觉障碍有关。

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本文引用的文献

1
The association of gustatory dysfunction, olfactory dysfunction, and cognition in older adults.
Int Forum Allergy Rhinol. 2023 Sep;13(9):1577-1583. doi: 10.1002/alr.23126. Epub 2023 Jan 18.
2
Ethical Guidelines for Publishing in the Annals of Geriatric Medicine and Research.
Ann Geriatr Med Res. 2022 Mar;26(1):1-3. doi: 10.4235/agmr.22.0021. Epub 2022 Mar 17.
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Effect of intensive olfactory training for cognitive function in patients with dementia.
Geriatr Gerontol Int. 2022 Jan;22(1):5-11. doi: 10.1111/ggi.14287. Epub 2021 Nov 8.
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Olfactory dysfunction is a risk factor for the comorbidity of mild cognitive impairment and Type 2 diabetes mellitus.
Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2021 Aug 28;46(8):831-837. doi: 10.11817/j.issn.1672-7347.2021.200046.
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Age-Related Olfactory Decline Is Associated With Levels of Exercise and Non-exercise Physical Activities.
Front Aging Neurosci. 2021 Jul 26;13:695115. doi: 10.3389/fnagi.2021.695115. eCollection 2021.

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