Department of Anesthesiology and Reanimation, Samsun University Faculty of Medicine, Samsun Training and Research Hospital, Samsun, Turkey.
Department of Orthopedics and Traumatology, Samsun University Faculty of Medicine, Samsun Training and Research Hospital, Samsun, Turkey.
Korean J Anesthesiol. 2024 Jun;77(3):364-373. doi: 10.4097/kja.23710. Epub 2024 Mar 14.
In recent years, the suprainguinal fascia iliaca compartment block (SFICB) has become more common in clinical practice. This assessor-blinded dose-finding study aimed to determine the minimum effective concentration (MEC90, MEC95) of bupivacaine for a single-injection SFICB in patients undergoing arthroscopic anterior cruciate ligament repair.
This prospective study was conducted at a tertiary hospital (postoperative recovery room and ward). The SFICB was performed as a postsurgical intervention after spinal anesthesia. Seventy patients were allocated using the biased-coin design up-and-down sequential method. The ultrasound-guided SFICB was performed using different bupivacaine concentrations, and standard multimodal analgesia was administered to all patients. Block success was defined as the absence of pain or presence of only tactile sensation during the pinprick test conducted on the anterior and lateral regions of the mid-thigh six hours postoperatively.
According to isotonic regression and bootstrap CIs, the MEC90 value of bupivacaine for a successful SFICB was 0.123% (95% CI [0.098, 0.191]) and the MEC95 value was 0.188% (95% CI [0.113, 0.223]).
Our study showed that the MEC90 and MEC95 values for bupivacaine administered via an SFICB for analgesia were 0.123% and 0.188%, respectively. One advantage of using lower concentrations of bupivacaine is the associated reduction in quadriceps weakness.
近年来，股外侧筋膜髂骨间隙阻滞（SFICB）在临床实践中越来越常见。本评估员盲法剂量探索研究旨在确定单次注射 SFICB 中布比卡因的最小有效浓度（MEC90、MEC95），用于接受关节镜前交叉韧带修复的患者。
这是一项在三级医院（术后恢复室和病房）进行的前瞻性研究。SFICB 在脊髓麻醉后作为术后干预进行。70 名患者采用偏置硬币设计上下序贯法分配。超声引导下进行 SFICB，并使用不同浓度的布比卡因，所有患者均给予标准多模式镇痛。阻滞成功定义为术后 6 小时行大腿前侧和外侧区针刺痛觉试验时无疼痛或仅存在触觉。
根据等渗回归和 bootstrap CI，布比卡因成功 SFICB 的 MEC90 值为 0.123%（95%CI [0.098, 0.191]），MEC95 值为 0.188%（95%CI [0.113, 0.223]）。
我们的研究表明，SFICB 中布比卡因的 MEC90 和 MEC95 分别为 0.123%和 0.188%。使用较低浓度布比卡因的一个优点是相关的股四头肌无力减少。
