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在前往初级保健中心的非糖尿病个体中,甘油三酯/葡萄糖指数及相关参数与印度糖尿病风险评分评估的比较——一项基于社区的横断面研究。

Comparison of triglyceride/glucose index and related parameters with Indian Diabetes Risk Score assessment in non-diabetic individuals visiting primary healthcare centre-A community-based cross-sectional study.

作者信息

Ramalingam Sivapragasam, Kar Amlan Kumar, Senthil Rajini

机构信息

Department of Community Medicine, Sri Lakshmi Narayana Institute of Medical Sciences, BIHER, Osudu, Agaram, Koodapakkam Post, Villianur Commune, Puducherry, India.

出版信息

J Family Med Prim Care. 2024 Jan;13(1):235-242. doi: 10.4103/jfmpc.jfmpc_996_23. Epub 2024 Feb 8.

Abstract

CONTEXT

Diabetes mellitus is a chronic metabolic disorder and has reached epidemic proportions in developing countries like India.

AIMS

Our study aimed to identify relationship between triglyceride glucose (TyG) index and related parameters with Indian diabetes risk score in non-diabetic individuals.

SETTINGS AND DESIGN

An analytical cross-sectional study was conducted in community at a primary healthcare centre attached to a medical college for six months from April 2022 to October 2022 after getting approval from institute ethical committee.

METHODS AND MATERIAL

We conducted a cross-sectional study at a primary healthcare centre attached to the medical college for six months duration with a sample size of 107, aged ≥18 years, which included apparently healthy individuals not diagnosed with any type of diabetes. Indian diabetes risk score (IDRS) scale was calculated along with anthropometric measurements and biochemical laboratory investigations like fasting triglyceride and fasting blood glucose.

RESULTS

Our study population included 53.3% male and 46.7% female; the mean age of male was 29.70 ± 12.26 and female was 34.28 ± 11.91. The mean TyG index for male and female was 8.48 ± 0.45 and 8.39 ± 0.52, respectively. 52.3% of our study population belonged to high-risk category, and 47.7% belonged to moderate-risk category. We also found positive correlation between TyG index and its related parameters and IDRS score. In linear regression between IDRS and TyG index, we found positive correlation, and in logistic regression showed for every 1 unit rise in age, there was 1.28 times increase in IDRS score ( < 0.001). TyG-WHtR was superior to other TyG-related parameters in identifying high IDRS score ( < 0.001).

CONCLUSIONS

TyG index and its related parameters can be used as a predictor in identifying diabetes mellitus along with IDRS score assessment in low-cost clinical settings like primary healthcare centre.

摘要

背景

糖尿病是一种慢性代谢紊乱疾病,在印度等发展中国家已达到流行程度。

目的

我们的研究旨在确定非糖尿病个体中甘油三酯葡萄糖(TyG)指数及相关参数与印度糖尿病风险评分之间的关系。

设置与设计

在获得学院伦理委员会批准后,于2022年4月至2022年10月在一所医学院附属的初级保健中心社区进行了一项分析性横断面研究,为期六个月。

方法与材料

我们在医学院附属的初级保健中心进行了为期六个月的横断面研究,样本量为107名年龄≥18岁的个体,其中包括未被诊断出患有任何类型糖尿病的明显健康个体。计算印度糖尿病风险评分(IDRS)量表,并进行人体测量和生化实验室检查,如空腹甘油三酯和空腹血糖。

结果

我们的研究人群中男性占53.3%,女性占46.7%;男性的平均年龄为29.70±12.26岁,女性为34.28±11.91岁。男性和女性的平均TyG指数分别为8.48±0.45和8.39±0.52。我们研究人群的52.3%属于高风险类别,47.7%属于中度风险类别。我们还发现TyG指数及其相关参数与IDRS评分之间存在正相关。在IDRS与TyG指数的线性回归中,我们发现存在正相关,在逻辑回归中显示,年龄每增加1个单位,IDRS评分增加1.28倍(P<0.001)。在识别高IDRS评分方面,TyG-WHtR优于其他TyG相关参数(P<0.001)。

结论

在初级保健中心等低成本临床环境中,TyG指数及其相关参数可与IDRS评分评估一起用作识别糖尿病的预测指标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e2af/10931890/621f23948d2a/JFMPC-13-235-g002.jpg

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