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加拿大转化衰老学研究领域的全景图:当前进展和未来方向的综合评估。

Navigating the Landscape of Translational Geroscience in Canada: A Comprehensive Evaluation of Current Progress and Future Directions.

机构信息

Department of Medicine, McGill University and Research Institute of the McGill University Health Centre, Montréal, Québec, Canada.

Schouela Centre of Excellence for Sustainable Health of Seniors (Schouela CEDurable), Montreal, Québec, Canada.

出版信息

J Gerontol A Biol Sci Med Sci. 2024 Jul 1;79(7). doi: 10.1093/gerona/glae069.

Abstract

The inaugural Canadian Conferences on Translational Geroscience were held as 2 complementary sessions in October and November 2023. The conferences explored the profound interplay between the biology of aging, social determinants of health, the potential societal impact of geroscience, and the maintenance of health in aging individuals. Although topics such as cellular senescence, molecular and genetic determinants of aging, and prevention of chronic disease were addressed, the conferences went on to emphasize practical applications for enhancing older people's quality of life. This article summarizes the proceeding and underscores the synergy between clinical and fundamental studies. Future directions highlight national and global collaborations and the crucial integration of early-career investigators. This work charts a course for a national framework for continued innovation and advancement in translational geroscience in Canada.

摘要

2023 年 10 月和 11 月,首届加拿大转化衰老学会议作为两个互补的会议举行。这些会议探讨了衰老生物学、健康的社会决定因素、衰老学的潜在社会影响以及衰老个体健康的维持之间的深刻相互作用。尽管涉及了细胞衰老、衰老的分子和遗传决定因素以及慢性疾病的预防等主题,但会议还强调了提高老年人生活质量的实际应用。本文总结了会议的进行情况,并强调了临床和基础研究之间的协同作用。未来的方向强调了国家和全球的合作以及早期职业研究人员的关键整合。这项工作为加拿大转化衰老学的持续创新和发展制定了国家框架。

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