CHANGE Research Working Group, Carrera de Medicina Humana, Facultad de Ciencias de la Salud, Universidad Científica del Sur, Lima, Perú.
Centro de Investigación del Envejecimiento (CIEN), Facultad de Medicina Humana, Universidad de San Martín de Porres, Lima, Perú.
Ann Geriatr Med Res. 2024 Jun;28(2):184-191. doi: 10.4235/agmr.23.0194. Epub 2024 Mar 15.
Sarcopenia is a musculoskeletal disease involving the reduction of muscle mass, strength, and performance. Handgrip strength (HGS) measurements included in frailty assessments are great biomarkers of aging and are related to functional deficits. We assessed the association between potential influencing factors and HGS asymmetry in older Peruvian adults.
We used a database of the Peruvian Naval Medical Center "Cirujano Santiago Távara" located in Callao, Peru. All the patients included were ≥60 years old and had an HGS measurement in the dominant and non-dominant hand.
From a total of 1,468 patients, 74.66% had HGS asymmetry. After adjustment, calf circumference weakness (adjusted prevalence ratio [aPR]=1.08; 95% confidence interval [CI], 1.01-1.15), falls risk (aPR = 1.08; 95% CI, 1.02-1.16), and an altered Lawton index (aPR=0.92; 95% CI, 0.84-0.99) were associated with HGS asymmetry.
Our findings suggest that HGS asymmetry should be measured along with other geriatric assessments used to evaluate health outcomes in the elderly to enhance health promotion and prevention aimed at preserving muscle strength to curb functional limitations in the elderly.
肌少症是一种涉及肌肉质量、力量和功能下降的肌肉骨骼疾病。握力（HGS）测量被纳入衰弱评估中，是很好的衰老生物标志物，与功能缺陷有关。我们评估了秘鲁老年人中潜在影响因素与 HGS 不对称性之间的关系。
我们使用了秘鲁海军医疗中心“Cirujano Santiago Távara”的数据库，该中心位于秘鲁卡亚俄。所有纳入的患者年龄均≥60 岁，且在优势手和非优势手上均进行了 HGS 测量。
在总共 1468 名患者中，74.66%存在 HGS 不对称。调整后，小腿围度无力（调整后的患病率比[aPR]=1.08；95%置信区间[CI]，1.01-1.15）、跌倒风险（aPR=1.08；95%CI，1.02-1.16）和 Lawton 指数改变（aPR=0.92；95%CI，0.84-0.99）与 HGS 不对称相关。
我们的研究结果表明，HGS 不对称性应与其他用于评估老年人健康结果的老年医学评估一起测量，以增强健康促进和预防措施，旨在保持肌肉力量，遏制老年人的功能限制。
