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早期环境如何影响发育中的大脑和长期心理健康。

How early environment influences the developing brain and long-term mental health.

作者信息

Sprooten Emma

机构信息

Department of Cognitive Neuroscience Donders Institute for Brain, Cognition and Behaviour Radboud University Medical Center Nijmegen The Netherlands.

Depertment of Human Genetics Radboud University Medical Center Nijmegen The Netherlands.

出版信息

JCPP Adv. 2024 Feb 28;4(1):e12230. doi: 10.1002/jcv2.12230. eCollection 2024 Mar.

DOI:10.1002/jcv2.12230
PMID:38486958
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10933647/
Abstract

The March 2024 issue of JCPP Advances features two neuroimaging studies that investigate links between early environmental risk factors for mental health problems, brain development and psychopathology in children and young adults. The papers provide new insights into how adverse environments and negative experiences in childhood increase risk for depression and mental health problems, and how this may or may not be mediated, or moderated, by individual differences in the brain.

摘要

《儿童与青少年精神药理学进展》2024年3月刊载了两项神经影像学研究，探讨了儿童和青少年心理健康问题的早期环境风险因素、大脑发育与精神病理学之间的联系。这些论文为童年时期的不良环境和负面经历如何增加抑郁症及心理健康问题的风险，以及这种风险如何可能或不可能由大脑的个体差异介导或调节提供了新的见解。

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本文引用的文献

1
Interplay of early negative life events, development of orbitofrontal cortical thickness and depression in young adulthood.早期负面生活事件、眶额皮质厚度发展与青年期抑郁之间的相互作用。
JCPP Adv. 2023 Dec 6;4(1):e12210. doi: 10.1002/jcv2.12210. eCollection 2024 Mar.
2
Parental education and income are linked to offspring cortical brain structure and psychopathology at 9-11 years.父母的教育程度和收入与9至11岁后代的大脑皮质结构及精神病理学有关。
JCPP Adv. 2024 Feb 6;4(1):e12220. doi: 10.1002/jcv2.12220. eCollection 2024 Mar.
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The next 10 years of behavioural genomic research.行为基因组学研究的未来十年。
JCPP Adv. 2022 Nov 4;2(4):e12112. doi: 10.1002/jcv2.12112. eCollection 2022 Dec.
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Why we need families in genomic research on developmental psychopathology.为何在发育性精神病理学的基因组研究中我们需要家庭。
JCPP Adv. 2023 Jan 27;3(1):e12138. doi: 10.1002/jcv2.12138. eCollection 2023 Mar.
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Effects of urban living environments on mental health in adults.城市居住环境对成年人心理健康的影响。
Nat Med. 2023 Jun;29(6):1456-1467. doi: 10.1038/s41591-023-02365-w. Epub 2023 Jun 15.
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Socioeconomic status and the developing brain - A systematic review of neuroimaging findings in youth.社会经济地位与大脑发育：青少年神经影像学研究的系统综述。
Neurosci Biobehav Rev. 2021 Nov;130:379-407. doi: 10.1016/j.neubiorev.2021.08.027. Epub 2021 Aug 30.
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The P-factor and its genomic and neural equivalents: an integrated perspective.P 因子及其基因组和神经等效物：综合视角。
Mol Psychiatry. 2022 Jan;27(1):38-48. doi: 10.1038/s41380-021-01031-2. Epub 2021 Feb 1.
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Inter-individual differences in human brain structure and morphology link to variation in demographics and behavior.个体间人脑结构和形态的差异与人口统计学和行为的变化有关。
Elife. 2019 Jul 3;8:e44443. doi: 10.7554/eLife.44443.
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The orbitofrontal cortex and emotion in health and disease, including depression.眶额皮质与健康和疾病中的情绪，包括抑郁症。
Neuropsychologia. 2019 May;128:14-43. doi: 10.1016/j.neuropsychologia.2017.09.021. Epub 2017 Sep 24.
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